merck millipore,默克密理博,448105,c-Met Kinase Inhibitor III

搜索"Merck Millipore 密理愽"产品

Merck Millipore 默克密理愽

merck millipore,默克密理博,448105,c-Met Kinase Inhibitor III - Calbiochem

经验配方
C₂₁H₁₇Cl₂FN₂O₂

描述
概述	A 6-Benzyloxyquinoline derivative which acts as an ATP-competitive inhibitor against c-Met (IC₅₀ = 9.3 nM), with more than 20 fold selectivity against a panel of 19 receptor tyrosine kinases and 8 serine/threonine kinases, in enzymatic assays. Also exhibits MKN45 cell growth inhibition (IC₅₀ = 93 nM) and displays HDG-dependent anti-proliferative activity (IC₅₀ = 300 nM) in HUVEC cultures, in vitro.
产品目录编号	448105
品牌系列	Calbiochem®
同义词	2-(6-((R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)quinolin-3-yl)cyclopropanecarboxamide

参考
参考	Nishii, H., et al. 2009. Bioorg. Med. Chem. Lett. 20, 1405.

生物信息
纯度	≥95% by HLPC

理化信息
溶解度	DMSO

储存和货运信息
货运代码	Shipped with Blue Ice or with Dry Ice
毒性	Standard Handling
储存	-20°C
无需冷冻	No
特殊指南	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

merck millipore,默克密理博,448105,c-Met Kinase Inhibitor III - Calbiochem

whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech