merck millipore,默克密理愽
  • merck millipore,默克密理博,444258,MMP-14 Substrate I, Fluorogenic - Calbiochem

  • merck millipore,默克密理博,444258,MMP-14 Substrate I, Fluorogenic - Calbiochem

    产品名称：MMP-14 Substrate I, Fluorogenic - Calbiochem
    产品型号：444258
    A specific fluorescence resonance energy transfer (FRET) peptide substrate for the detection of MMP activity.

    merck millipore,默克密理博,444258,MMP-14 Substrate I, Fluorogenic - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,444258,MMP-14 Substrate I, Fluorogenic - Calbiochem

    重要规格表
    描述
    概述 A specific fluorescence resonance energy transfer (FRET) peptide substrate for the detection of MMP activity. (kcat/Km = 7.3 x 105 M-1s-1 for MMP-14 (MT1-MMP) and 3.6 x 104 M-1s-1 for MMP-11 at 25°C, pH 7.5).
    产品目录编号 444258
    品牌系列 Calbiochem®
    同义词 MT1-MMP Substrate I, Fluorogenic, MCA-PLA-C(OMeBz)-WAR(Dpa)-NH₂
    参考
    参考 Mucha, A., et al. 1998. J. Biol. Chem. 273, 2763.
    产品信息
    具有ATP竞争性 N
    形式 Yellow lyophilized solid
    配方 Supplied as a trifluoroacetate salt.
    Hill配方 C₆₆H₈₂N₁₆O₁₇S
    化学配方 C₆₆H₈₂N₁₆O₁₇S
    Molar Mass 1403.5
    肽序列 MCA-Pro-Leu-Ala-Cys(p-OMeBz)-Trp-Ala-Arg(Dpa)-NH₂ Dpa = N³-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl, Bz = Benzyl
    可逆 N
    生物信息
    主靶 MMP-14
    主靶IC50 kcat/Km = 7.3 x 105 M-1s-1 for MMP-14; .6 x 104 M-1s-1 for MMP-11
    纯度 ≥97% by HPLC
    理化信息
    细胞可渗透 N
    最大排放 ~400 nm
    最大激励 ~328 nm
    溶解度 DMSO
    肽序列 MCA-Pro-Leu-Ala-Cys(p-OMeBz)-Trp-Ala-Arg(Dpa)-NH₂ Dpa = N³-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl, Bz = Benzyl
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,444258,MMP-14 Substrate I, Fluorogenic - Calbiochem

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