merck millipore,默克密理愽
  • merck millipore,默克密理博,444256,MMP Substrate III, Fluorogenic - Calbiochem

  • merck millipore,默克密理博,444256,MMP Substrate III, Fluorogenic - Calbiochem

    产品名称：MMP Substrate III, Fluorogenic - Calbiochem
    产品型号：444256
    A specific fluorogenic resonance energy transfer (FRET) peptide substrate with an MMP cleavable Gly-Leu bond and EDANS/Dabcyl as fluorophore/quencher combination.

    merck millipore,默克密理博,444256,MMP Substrate III, Fluorogenic - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,444256,MMP Substrate III, Fluorogenic - Calbiochem

    重要规格表
    描述
    概述 A specific fluorogenic resonance energy transfer (FRET) peptide substrate with an MMP cleavable Gly-Leu bond and EDANS/Dabcyl as fluorophore/quencher combination. Useful for the detection of MMP activity [kcat/Km = 619,000 M-1s-1 for MMP-2, 206,000 M-1s-1 for MMP-9, 40,000 M-1s-1 for MMP-3, and 21,000 M-1s-1 for MMP-1; at 37°C, pH 7.6 ]. Exhibits a high degree of sensitivity that is not affected by optical disturbances in biological media. Also useful for MMP activity measurements in synovial fluid and culture medium.
    产品目录编号 444256
    品牌系列 Calbiochem®
    同义词 DABCYL-GABA-PQGL-E(EDANS)-AK-NH₂, TNO211
    参考
    参考 Beekman, B., et al. 1996. FEBS Lett 390, 221.
    产品信息
    具有ATP竞争性 N
    形式 Red lyophilized solid
    配方 Supplied as a trifluoroacetate salt.
    Hill配方 C₆₃H₈₈N₁₆O₁₄S
    化学配方 C₆₃H₈₈N₁₆O₁₄S
    Molar Mass 1325.6
    肽序列 DABCYL-GABA-Pro-Gln-Gly-Leu-Glu(EDANS)-Ala-Lys-NH₂
    可逆 N
    生物信息
    主靶 Detection of MMP activity
    纯度 ≥97% by HPLC
    理化信息
    细胞可渗透 N
    最大排放 ~485 nm
    最大激励 ~340 nm
    溶解度 DMSO
    肽序列 DABCYL-GABA-Pro-Gln-Gly-Leu-Glu(EDANS)-Ala-Lys-NH₂
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,444256,MMP Substrate III, Fluorogenic - Calbiochem

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