merck millipore,默克密理愽
  • merck millipore,默克密理博,444249,MMP-2/MMP-9 Inhibitor II - CAS 193807-60-2 - Calbiochem

  • merck millipore,默克密理博,444249,MMP-2/MMP-9 Inhibitor II - CAS 193807-60-2 - Calbiochem

    产品名称：MMP-2/MMP-9 Inhibitor II - CAS 193807-60-2 - Calbiochem
    产品型号：444249
    The MMP-2/MMP-9 Inhibitor II, also referenced under CAS 193807-60-2, controls the biological activity of MMP-2/MMP-9. This small molecule/inhibitor is primarily used for Protease Inhibitors applicatio More>>

    merck millipore,默克密理博,444249,MMP-2/MMP-9 Inhibitor II - CAS 193807-60-2 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,444249,MMP-2/MMP-9 Inhibitor II - CAS 193807-60-2 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₁H₂₀N₂O₄S193807-60-2
    描述
    概述 A potent inhibitor of MMP-2 (IC50 = 17 nM) and MMP-9 (IC50 = 30 nM). Also shown to potently induce and rapidly activate HIF. Reported to inhibit Lewis lung carcinoma-induced lung colonization in a murine model.
    产品目录编号 444249
    品牌系列 Calbiochem®
    同义词 (2R)-[(4-Biphenylylsulfonyl)amino]-N-hydroxy-3-phenylpropionamide, BiPS, BiPS
    参考
    参考 Lauzier, M.C., et al. 2008. Mol. Pharmacol. In press.
    Mifune, M., et al. 2005. J. Biol. Chem. 280, 26592.
    Zhang, H., et al. 2004. Circ. Res. 95, 989.
    Tamura, Y., et al. 1998. J. Med. Chem. 41, 640.
    产品信息
    CAS号 193807-60-2
    具有ATP竞争性 N
    形式 Off-white solid
    Hill配方 C₂₁H₂₀N₂O₄S
    化学配方 C₂₁H₂₀N₂O₄S
    Molar Mass 396.5
    可逆 N
    结构配方图像
    生物信息
    主靶 MMP-2
    主靶IC50 17 nM, 30 nM against MMP-2, and MMP-9, respectively
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 DMSO or MeOH
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,444249,MMP-2/MMP-9 Inhibitor II - CAS 193807-60-2 - Calbiochem

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