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merck millipore,默克密理博,420139,JAK2 Inhibitor IV - CAS 1110502-30-1 - Calbiochem
产品名称:JAK2 Inhibitor IV - CAS 1110502-30-1 - Calbiochem
产品型号:420139
The JAK2 Inhibitor IV, also referenced under CAS 1110502-30-1, controls the biological activity of JAK2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applica More>>
merck millipore,默克密理博,420139,JAK2 Inhibitor IV - CAS 1110502-30-1 - Calbiochem
- 产品介绍
重要规格表
经验配方 CAS号 C₁₇H₂₀N₄O₂S 1110502-30-1 描述 概述 An aminoindazole compound that potently inhibits the activity of both the wild-type JAK2 and the constitutively active V617F mutant (IC50 = 78 and 206 nM, respectively) frequently found in patients with clonal polycythemia vera, essential thrombocytosis, and chronic idiopathic myelofibrosis, while exhibiting much reduced activity against JAK3 (IC50 = 2.93 µM). 产品目录编号 420139 品牌系列 Calbiochem®
同义词 3-Amino-5-(N-tert-butylsulfonamido-4-phenyl)-indazole 参考 参考 Antonysamy, S., et al. 2008. Bioorg. Med. Chem. Lett. 19, 279. 产品信息 CAS号 1110502-30-1 形式 Pale yellow solid Hill配方 C₁₇H₂₀N₄O₂S 化学配方 C₁₇H₂₀N₄O₂S Molar Mass 344.4 结构配方图像 生物信息 纯度 ≥97% by HPLC 理化信息 溶解度 DMSO or EtOH 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 +2°C to +8°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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