• merck millipore,默克密理博,420139,JAK2 Inhibitor IV - CAS 1110502-30-1 - Calbiochem
  • merck millipore,默克密理博,420139,JAK2 Inhibitor IV - CAS 1110502-30-1 - Calbiochem

    产品名称:JAK2 Inhibitor IV - CAS 1110502-30-1 - Calbiochem
    产品型号:420139
    The JAK2 Inhibitor IV, also referenced under CAS 1110502-30-1, controls the biological activity of JAK2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applica More>>

    merck millipore,默克密理博,420139,JAK2 Inhibitor IV - CAS 1110502-30-1 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,420139,JAK2 Inhibitor IV - CAS 1110502-30-1 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₇H₂₀N₄O₂S1110502-30-1
    描述
    概述 An aminoindazole compound that potently inhibits the activity of both the wild-type JAK2 and the constitutively active V617F mutant (IC50 = 78 and 206 nM, respectively) frequently found in patients with clonal polycythemia vera, essential thrombocytosis, and chronic idiopathic myelofibrosis, while exhibiting much reduced activity against JAK3 (IC50 = 2.93 µM).
    产品目录编号 420139
    品牌系列 Calbiochem®
    同义词 3-Amino-5-(N-tert-butylsulfonamido-4-phenyl)-indazole
    参考
    参考 Antonysamy, S., et al. 2008. Bioorg. Med. Chem. Lett. 19, 279.
    产品信息
    CAS号 1110502-30-1
    形式 Pale yellow solid
    Hill配方 C₁₇H₂₀N₄O₂S
    化学配方 C₁₇H₂₀N₄O₂S
    Molar Mass 344.4
    结构配方图像
    生物信息
    纯度 ≥97% by HPLC
    理化信息
    溶解度 DMSO or EtOH
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,420139,JAK2 Inhibitor IV - CAS 1110502-30-1 - Calbiochem

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