merck millipore,默克密理博,407950,Ionomycin, Free Acid, Streptomyces conglobatus - CAS 56092-81-0

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merck millipore,默克密理博,407950,Ionomycin, Free Acid, Streptomyces conglobatus - CAS 56092-81-0 - Calbiochem
产品名称：Ionomycin, Free Acid, Streptomyces conglobatus - CAS 56092-81-0 - Calbiochem
产品型号：407950
Highly specific for divalent cations and more effective than A23187 as a mobile ion carrier for Ca2+.

merck millipore,默克密理博,407950,Ionomycin, Free Acid, Streptomyces conglobatus - CAS 56092-81-0 - Calbiochem

产品介绍

merck millipore,默克密理博,407950,Ionomycin, Free Acid, Streptomyces conglobatus - CAS 56092-81-0 - Calbiochem

重要规格表

经验配方	CAS号
C₄₁H₇₂O₉	56092-81-0

描述
概述	Highly specific for divalent cations and more effective than A23187 (Cat. No. 100105) as a mobile ion carrier for Ca²⁺. Complexes with Ca²⁺between pH 7 and 9.5. In contrast to A23187, it is not fluorescent. Useful for studies of Ca²⁺ transport across biological membranes and measurement of cytoplasmic free Ca²⁺. Induces apoptotic neuronal degeneration in embryonic cortical neurons and cell cycle arrest in the G₁ phase in mature Burkitt lymphoma cell lines.
概述	Absorption max. (280 nm, MeOH): 18,600 M^-1cm^-1.
产品目录编号	407950
品牌系列	Calbiochem®

参考
参考	Aagaard-Tillery, K.M., and Jelinek, D.F. 1995. J. Immunol. 155, 3297. Takei, N., and Endo, Y. 1994. Brain Res. 652, 65. Dupuy d’Angeac, A., et al. 1993. J. Cell Physiol. 154, 44. Lee, H.C. 1993. J. Biol. Chem. 268, 293. Kuznetsov, G., et al. 1992. J. Biol. Chem. 267, 3932. Toeplitz, B.K., et al. 1979. J. Am. Chem. Soc. 101, 3344. Liu, C.M., and Hermann, T.E. 1978. J. Biol. Chem. 253, 5892.

参考

Aagaard-Tillery, K.M., and Jelinek, D.F. 1995. J. Immunol. 155, 3297.
Takei, N., and Endo, Y. 1994. Brain Res. 652, 65.
Dupuy d’Angeac, A., et al. 1993. J. Cell Physiol. 154, 44.
Lee, H.C. 1993. J. Biol. Chem. 268, 293.
Kuznetsov, G., et al. 1992. J. Biol. Chem. 267, 3932.
Toeplitz, B.K., et al. 1979. J. Am. Chem. Soc. 101, 3344.
Liu, C.M., and Hermann, T.E. 1978. J. Biol. Chem. 253, 5892.

产品信息
CAS号	56092-81-0
具有ATP竞争性	N
形式	Waxy solid
Hill配方	C₄₁H₇₂O₉
化学配方	C₄₁H₇₂O₉
Molar Mass	709.0
可逆	N
结构配方图像

生物信息
主靶	Mobile ion carrier for Ca2+
纯度	≥90% by HPLC

理化信息
细胞可渗透	N
溶解度	DMSO or MeOH

GHS安全信息
RTECS	NO0600000

安全信息
R相	R: 22 Harmful if swallowed.
S相	S: 36 Wear suitable protective clothing.

储存和货运信息
货运代码	Ambient Temperature Only
毒性	Harmful
储存	+2°C to +8°C
避光	Protect from light
无需冷冻	No
特殊指南	Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 1 year at 4°C.