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品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABS606 描述 Anti-ACSL1 Antibody Alternate Names - ACSL1
- Long-chain-fatty-acid--CoA ligase 1
- Acyl-CoA synthetase 1
- ACS1
- Long-chain acyl-CoA synthetase 1
- LACS 1
- Long-chain acyl-CoA synthetase 2
- LACS 2
- Long-chain fatty acid-CoA ligase 2
- Palmitoyl-CoA ligase 1
- Palmitoyl-CoA ligase 2
背景信息 The protein named Long-chain-fatty-acid--CoA ligase 1 or alternatively Acyl-CoA synthetase 1, (ACS1), Long-chain acyl-CoA synthetase 1, (LACS 1), Long-chain acyl-CoA synthetase 2, (LACS 2) Long-chain fatty acid-CoA ligase 2, Palmitoyl-CoA ligase 1 or Palmitoyl-CoA ligase 2 and encoded by the human gene named ACSL1/FACL1/FACL2/LACS/LACS1/LACS2 is localized in the mitochondria of most cells and can also be found in the peroxisomes and endoplasmic reticulum membranes. ACSL1 catalyzes the activation of long chain fatty acids and coenzyme A (CoA) to form activated acyl-CoA entities ready for biosynthetic or catabolic pathways. ACSL1 synthesizes the first step in fatty acid metabolism by converting long chain fatty acids in acyl-CoA thioesters. Acyl-CoA’s enter both anabolic and catabolic pathways and the disturbance of these pathways is linked to disorders such as hepatic steatosis, hyperlipidemia and insulin resistance. ACSL1 is one of five isoforms of Acyl-CoA synthetases. Anti-ACSL1 rabbit polyclonal antibody has been tested in western blot on HepG2 cell extracts. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide and 50% glycerol. 应用 应用 Detect Long-chain-fatty-acid--CoA ligase 1 using this rabbit polyclonal antibody, Anti-ACSL1 Antibody validated for use in western blotting. 主要应用 - Western Blotting
生物信息 免疫原品种 GST-tagged fusion protein corresponding to human ACSL1. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Human 抗体类型 Polyclonal Antibody 基因符号 - LACS2
- ACSL1
- FACL1
- FACL2
- LACS
- LACS1
纯化方法 Antigen Affinity purified UniProt编号 - P33121
产品使用声明 质量保证 Evaluated by Western Blotting in HepG2 cell lysate.
Western Blotting Analysis: A 1:800 dilution of this antibody detected ACSL1 in HepG2 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.包装信息 数量 150 µL
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