merck millipore,默克密理愽
  • merck millipore,默克密理博,407616,IL-1R Antagonist - CAS 566914-00-9 - Calbiochem

  • merck millipore,默克密理博,407616,IL-1R Antagonist - CAS 566914-00-9 - Calbiochem

    产品名称：IL-1R Antagonist - CAS 566914-00-9 - Calbiochem
    产品型号：407616
    The IL-1R Antagonist, also referenced under CAS 566914-00-9, controls the biological activity of IL-1R.

    merck millipore,默克密理博,407616,IL-1R Antagonist - CAS 566914-00-9 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,407616,IL-1R Antagonist - CAS 566914-00-9 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₈H₂₆N₂O₂566914-00-9
    描述
    概述 A cell-permeable, end protected L-valyl derivative modeled on the MyD88-binding sequence of the TIR (Toll/IL-1R/resistance) domain BB-loop of IL-1RI (type I IL-1 receptor). It specifically inhibits TIR domain-mediated MyD88/IL1-RI interaction without affecting TLR4/MyD88 interaction. It was used successfully to reduce IL-1β-induced fever in mice in vivo and to attenuate IL-1β-induced, but not LPS-induced, activation of MAP kinase signaling cascades in murine lymphocytes and EL4 thymoma cells in vitro.
    产品目录编号 407616
    品牌系列 Calbiochem®
    同义词 BB-loop Mimic, Hydrocinnamoyl-L-valyl Pyrrolidine, TIR Domain Mimic
    参考
    参考 Bartfai, T., et al. 2003. Proc. Natl. Acad. Sci. USA 100, 7971.
    产品信息
    CAS号 566914-00-9
    具有ATP竞争性 N
    形式 Colorless oil
    Hill配方 C₁₈H₂₆N₂O₂
    化学配方 C₁₈H₂₆N₂O₂
    Molar Mass 302.4
    可逆 N
    结构配方图像
    生物信息
    主靶 TIR domain-mediated MyD88/IL1-RI interaction
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO or EtOH
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,407616,IL-1R Antagonist - CAS 566914-00-9 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,345883,GGTI-298 - CAS 180977-44-0 - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,SF-1308,NUMA; Ms, Cyanine 5 RNA Detection Probe,SmartFlare


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