merck millipore,默克密理愽
  • merck millipore,默克密理博,407602,InSolution™ Interleukin-1 Receptor-Associated-Kinase-1/4 Inhibitor - CAS 509093-47-4 - Calbiochem

  • merck millipore,默克密理博,407602,InSolution™ Interleukin-1 Receptor-Associated-Kinase-1/4 Inhibitor - CAS 509093-47-4 - Calbiochem

    产品名称：InSolution™ Interleukin-1 Receptor-Associated-Kinase-1/4 Inhibitor - CAS 509093-47-4 - Calbiochem
    产品型号：407602
    The Interleukin-1 Receptor-Associated-Kinase-1/4 Inhibitor controls the activity of Interleukin-1 Receptor-Associated-Kinase-1/4. Primarily used for Phosphorylation & Dephosphorylation apps.

    merck millipore,默克密理博,407602,InSolution™ Interleukin-1 Receptor-Associated-Kinase-1/4 Inhibitor - CAS 509093-47-4 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,407602,InSolution™ Interleukin-1 Receptor-Associated-Kinase-1/4 Inhibitor - CAS 509093-47-4 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₀H₂₁N₅O₄509093-47-4
    描述
    概述 A cell-permeable benzimidazole compound that acts as a potent and selective inhibitor of interleukin-1 receptor-associated kinases (IC50 = 300 nM and 200 nM for IRAK-1 and -4). Shown to exhibit little activity against a panel of 27 other kinases (IC50 >10 µM), including lck and src. The solid form of this compound (Cat. No. 407601) is also available.
    产品目录编号 407602
    品牌系列 Calbiochem®
    同义词 N-(2-Morpholinylethyl)-2-(3-nitrobenzoylamido)-benzimidazole, N-(1-(2-morpholinoethyl)-1H-benzo[d]imidazol-2-yl)-3-nitrobenzamide
    参考
    参考 Srivastava, R., et al. 2012. Cancer Res. 72, In press.
    Bhattacharyya, S., et al. 2007. Am. J. Physiol. Gastrointest. Liver Physiol. 293, G429.
    Powers, J.P., et al. 2006. Bioorg. Med. Chem. Lett. 16, 2842.
    产品信息
    CAS号 509093-47-4
    形式 Liquid
    配方 A 25 mM (5 mg/506 µL) solution of Interleukin-1 Receptor-Associated-Kinase-1/4 Inhibitor (Cat. No. 407601) in DMSO.
    Hill配方 C₂₀H₂₁N₅O₄
    Molar Mass 395.4
    吸湿 Hygroscopic
    可逆 Y
    结构配方图像
    生物信息
    主靶 IRAK-1/4
    主靶IC50 300 nM and 200 nM for IRAK-1 and -4
    纯度 ≥98% by HPLC
    安全信息
    R相 R: 36/38

    Irritating to eyes and skin.
    储存和货运信息
    货运代码 Dry Ice Only
    毒性 Irritant
    储存 ≤ -70°C
    避光 Protect from light
    吸湿 Hygroscopic
    避免冻结 / 解冻 Avoid freeze/thaw
    无需冷冻 No
    特殊指南 Following initial thaw, aliquot and freeze (-70°C). Aliquots are stable for up to 6 months at -70°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,407602,InSolution™ Interleukin-1 Receptor-Associated-Kinase-1/4 Inhibitor - CAS 509093-47-4 - Calbiochem

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