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经验配方 CAS号 C₃₀H₁₆O₈ 548-04-9 描述 概述 Polycyclic dione that has anti-retroviral activity. Inhibits protein kinase C (IC50 = 3.3 μM). Also known to inhibit casein kinase II (IC50 = 6 nM), MAP kinase (IC50 = 4 nM), and the protein tyrosine activities of the insulin receptor (IC50 = 20-29 nM) and the epidermal growth factor receptor (IC50 = 35 nM). 产品目录编号 400076 品牌系列 Calbiochem®
同义词 Casein Kinase II Inhibitor XI 参考 参考 Zhang, W., et al. 1997. Cancer Lett. 120, 31.
Agostinis, P., et al. 1995. Biochem. Pharmacol. 49, 1615.
Frew, T., et al. 1994. Anticancer Res. 14, 2425.
Barnard, D.L., et al. 1992. Antiviral Res. 17, 63.
Takahashi, I., et al. 1989. Biochem. Biophys. Res. Commun. 165, 1207.产品信息 CAS号 548-04-9 具有ATP竞争性 N 形式 Black solid Hill配方 C₃₀H₁₆O₈ 化学配方 C₃₀H₁₆O₈ Molar Mass 504.5 可逆 N 结构配方图像 生物信息 主靶 PKC 主靶IC50 3.3 µM, 6 nM, 4 nM, 20-29 nM , 35 nM, against protein kinase C, casein kinase II, MAP kinase, the protein tyrosine activities of the insulin receptor, and the epidermal growth factor receptor, respectively 纯度 ≥95% by 1H NMR 理化信息 细胞可渗透 N 溶解度 DMSO, EtOH, or MeOH 安全信息 R相 R: 22
Harmful if swallowed.S相 S: 22-36
Do not breathe dust.
Wear suitable protective clothing.储存和货运信息 货运代码 Ambient Temperature Only
毒性 Harmful
储存 +2°C to +8°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
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