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merck millipore,默克密理博,376816,Hexokinase II VDAC Binding Domain Peptide, Cell-Permeable - Calbiochem
产品名称：Hexokinase II VDAC Binding Domain Peptide, Cell-Permeable - Calbiochem
产品型号：376816
A cell-permeable peptide analog of Hexokinase II VDAC binding domain peptide.
merck millipore,默克密理博,376816,Hexokinase II VDAC Binding Domain Peptide, Cell-Permeable - Calbiochem
- 产品介绍
重要规格表
经验配方 C₁₈₈H₂₉₁N₅₃O₄₀S₂ 描述 概述 A cell-permeable peptide analog of Hexokinase II VDAC binding domain peptide (Cat. No. 376815). The internalization domain of the Antennapedia homeoprotein is fused to the methionine amino terminal. Shown to completely detach and translocate HXK2 from mitochondria to the cytosol in HeLa cells at 100 µM. Does not induce Bax translocation or cytochrome c release when used alone. However, it markedly sensitizes cells to cytochrome c release and to the induction of apoptosis when used in combination with a Bax-dependent apoptosis inducer, Indomethacin (Cat. No. 405268). 产品目录编号 376816 品牌系列 Calbiochem®
同义词 HXK2VBD-cpm, H-RQIKIWFQNRRMKWKK-MIASHLLAYFFTELN-NH₂ 参考 参考 Pastorino, J.G., et al. 2002. J. Biol. Chem. 277, 7610.
Holinger, E.P., et al. 1999. J. Biol. Chem. 274, 13298.
Sui, D., and Wilson, J.E. 1997. Arch. Biochem. Biophys. 345, 111.产品信息 具有ATP竞争性 N 形式 White lyophilized solid 配方 Supplied as a trifluoroacetate salt. Hill配方 C₁₈₈H₂₉₁N₅₃O₄₀S₂ 化学配方 C₁₈₈H₂₉₁N₅₃O₄₀S₂ Molar Mass 3997.8 吸湿 Hygroscopic
肽序列 H-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-Met-Ile-Ala-Ser-His-Leu-Leu-Ala-Tyr-Phe-Phe-Thr-Glu-Leu-Asn-NH₂ 可逆 N 生物信息 主靶 Detach and translocate HXK2 from mitochondria to the cytosol 纯度 ≥95% by HPLC 理化信息 细胞可渗透 Y 溶解度 H₂O 肽序列 H-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-Met-Ile-Ala-Ser-His-Leu-Leu-Ala-Tyr-Phe-Phe-Thr-Glu-Leu-Asn-NH₂ 储存和货运信息 货运代码 Blue Ice Only
毒性 Standard Handling
储存 -20°C
避光 Protect from light
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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