merck millipore,默克密理博,371962,InSolution™ H-89, Dihydrochloride

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merck millipore,默克密理博,371962,InSolution™ H-89, Dihydrochloride - Calbiochem
产品名称：InSolution™ H-89, Dihydrochloride - Calbiochem
产品型号：371962

merck millipore,默克密理博,371962,InSolution™ H-89, Dihydrochloride - Calbiochem

产品介绍

merck millipore,默克密理博,371962,InSolution™ H-89, Dihydrochloride - Calbiochem

重要规格表

经验配方
C₂₀H₂₀BrN₃O₂S

描述
产品目录编号	371962
品牌系列	Calbiochem®
同义词	N-[2-((p-Bromocinnamyl)amino)ethyl]-5-isoquinolinesulfonamide, 2HCl, PKA Inhibitor III

参考
参考	Leemhuis, J., et al. 2002. J. Pharmacol. Exp. Ther. 300, 1000. Davies, S.P. et al. 2000. Biochem. J. 351, 95. de Rooij, J., et al. 1998. Nature. 396, 474. Kawasaki, H., et al. 1998. Science. 282, 2275. Findik, D., et al. 1995. J. Cell. Biochem. 57, 12. Hidaka, H., and Kobayashi, R. 1992. Annu. Rev. Pharmacol. Toxicol. 32, 377. Geilen, C.C., et al. 1992. FEBS Lett. 309, 381. Chijiwa, T., et al. 1990. J. Biol. Chem. 265, 5267. Combest, W.L., et al. 1988. J. Neurochem. 51, 1581.

参考

Leemhuis, J., et al. 2002. J. Pharmacol. Exp. Ther. 300, 1000.
Davies, S.P. et al. 2000. Biochem. J. 351, 95.
de Rooij, J., et al. 1998. Nature. 396, 474.
Kawasaki, H., et al. 1998. Science. 282, 2275.
Findik, D., et al. 1995. J. Cell. Biochem. 57, 12.
Hidaka, H., and Kobayashi, R. 1992. Annu. Rev. Pharmacol. Toxicol. 32, 377.
Geilen, C.C., et al. 1992. FEBS Lett. 309, 381.
Chijiwa, T., et al. 1990. J. Biol. Chem. 265, 5267.
Combest, W.L., et al. 1988. J. Neurochem. 51, 1581.

产品信息
具有ATP竞争性	N
形式	Liquid
配方	A 10 mM (1 mg/193 µl) solution of H-89, 2HCl (Cat. No. 371963) in DMSO.
Hill配方	C₂₀H₂₀BrN₃O₂S
化学配方	C₂₀H₂₀BrN₃O₂S
Molar Mass	519.3
可逆	N
结构配方图像

生物信息
主靶	PKA
主靶K_i	48 nM against protein kinase A
纯度	≥99% by HPLC

理化信息
细胞可渗透	N

安全信息
R相	R: 36/38 Irritating to eyes and skin.
S相	S: 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

储存和货运信息
货运代码	Blue Ice Only
毒性	Irritant
储存	-20°C
避光	Protect from light
无需冷冻	No
特殊指南	Following initial thaw, aliquot and freeze (-20°C).