merck millipore,默克密理愽
  • merck millipore,默克密理博,371830,GPR40 Antagonist, GW1100 - CAS 306974-70-9 - Calbiochem

  • merck millipore,默克密理博,371830,GPR40 Antagonist, GW1100 - CAS 306974-70-9 - Calbiochem

    产品名称：GPR40 Antagonist, GW1100 - CAS 306974-70-9 - Calbiochem
    产品型号：371830
    The GPR40 Antagonist, GW1100, also referenced under CAS 306974-70-9, controls the biological activity of GPR40. This small molecule/inhibitor is primarily used for Biochemicals applications.

    merck millipore,默克密理博,371830,GPR40 Antagonist, GW1100 - CAS 306974-70-9 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,371830,GPR40 Antagonist, GW1100 - CAS 306974-70-9 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₇H₂₅FN₄O₄S306974-70-9
    描述
    概述 A cell-permeable pyrimidinylmethyl-pyrimidinone compound that acts as potent, reversible and non-competitive GPR40 antagonist. Selectively blocks GPR40-mediated intracellular Ca2+ release stimulated by GPR40 Agonist GW9508 (Cat. No. 371706) and linoleic acid (pIC50 of 5.99 in GPR40 expressing HEK293 cells) with no effect on GPR120-mediated activation. Shown to significantly reverse glucose-induced insulin secretion potentiated by GW9508 and only partially reduce linoleic acid effect in MIN6 cells.
    产品目录编号 371830
    品牌系列 Calbiochem®
    同义词 1-(4-Ethoxycarbonylphenyl)-2-(4-fluorobenzylthio)-5-(2-ethoxy-5-pyrimidinylmethyl)-4-pyrimidinone, SB376752
    参考
    参考 Stoddart, L.A., et al. 2007. Mol. Pharmacol. 71, 994.
    Briscoe, C.P., et al. 2006. Br. J. Pharmacol. 148, 619.
    产品信息
    CAS号 306974-70-9
    形式 White powder
    Hill配方 C₂₇H₂₅FN₄O₄S
    化学配方 C₂₇H₂₅FN₄O₄S
    Molar Mass 520.6
    结构配方图像
    生物信息
    纯度 ≥97% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,371830,GPR40 Antagonist, GW1100 - CAS 306974-70-9 - Calbiochem

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下一件merck millipore产品：merck millipore,默克密理博,AG303,MCT6, control peptide for AB3554P


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