- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
-
-
merck millipore,默克密理博,371818,G-Protein βγ Binding Peptide, mSIRK - Calbiochem
产品名称：G-Protein βγ Binding Peptide, mSIRK - Calbiochem
产品型号：371818
A cell-permeable, N-myristoylated G-protein βγ selective binding peptide that disrupts the interaction between α and βγ subunits and promotes the α subunit dissociation without stimulating nucleotide More>>
merck millipore,默克密理博,371818,G-Protein βγ Binding Peptide, mSIRK - Calbiochem
- 产品介绍
重要规格表
经验配方 C₉₃H₁₅₀N₂₀O₂₅ 描述 概述 A cell-permeable, N-myristoylated G-protein βγ selective binding peptide that disrupts the interaction between α and βγ subunits and promotes the α subunit dissociation without stimulating nucleotide exchange. Shown to cause a rapid activation of ERK1/2 (EC50 ~ 2.5 - 5 µM) in rat arterial smooth muscle and Rat2 cells. Also promotes the phosphorylation of JNK and p38 MAP kinase, phospholipase C and causes Ca2+ release from internal stores. Negative control is also available (Cat. No. 371820). 产品目录编号 371818 品牌系列 Calbiochem®
同义词 mSIRK, myr-SIRKALNILGYPDYD-OH 参考 参考 Goubaeva, F., et al. 2003. J. Biol. Chem. 278, 19634.
Scott, J.K., et al. 2001. EMBO J. 20, 767.产品信息 具有ATP竞争性 N 形式 Lyophilized 配方 Supplied as a trifluoroacetate salt. Hill配方 C₉₃H₁₅₀N₂₀O₂₅ 化学配方 C₉₃H₁₅₀N₂₀O₂₅ Molar Mass 1948.3 吸湿 Hygroscopic
肽序列 Myr-N-Ser-Ile-Arg-Lys-Ala-Leu-Asn-Ile-Leu-Gly-Tyr-Pro-Asp-Tyr-Asp-OH 可逆 N 生物信息 主靶 N-myristoylated G-protein βγ selective binding 主靶IC50 EC50 ~ 2.5 - 5 µM in activation of ERK1/2 in rat arterial smooth muscle and Rat2 cells 纯度 ≥95% by HPLC 理化信息 细胞可渗透 Y 溶解度 DMSO 肽序列 Myr-N-Ser-Ile-Arg-Lys-Ala-Leu-Asn-Ile-Leu-Gly-Tyr-Pro-Asp-Tyr-Asp-OH 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 +2°C to +8°C
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C 包装信息 惰性气体下包装 Packaged under inert gas
上一件merck millipore产品：merck millipore,默克密理博,MAB19562X,Anti-Laminin-5 Antibody, clone D4B5, Alexa Fluor 488 conjugated
下一件merck millipore产品：merck millipore,默克密理博,194430,ABTS™ Chromophore, Diammonium Salt
相关产品
merck millipore,默克密理博,MAB4327,Anti-Axin-1 Antibody, clone 3F4.2
merck millipore,默克密理博,513028,PD 166285 - CAS 212391-63-4 - Calbiochem
merck millipore,默克密理博,70556,pET-41a(+) DNA - Novagen
merck millipore,默克密理博,124034,Akt Inhibitor XV, Isozyme-Selective - Calbiochem
merck millipore,默克密理博,MAB19562X,Anti-Laminin-5 Antibody, clone D4B5, Alexa Fluor 488 conjugated
merck millipore,默克密理博,194430,ABTS™ Chromophore, Diammonium Salt
merck millipore,默克密理博,69871,pET-29a(+) DNA - Novagen
merck millipore,默克密理博,MAB8257F-5,Anti-Influenza A Antibody, nucleoprotein, clone A1
merck millipore,默克密理博,03-231,Beclin 1 (Human) Recombinant Protein
merck millipore,默克密理博,06-822,Anti-phospho-PKCα (Ser657) Antibody