merck millipore,默克密理愽
  • merck millipore,默克密理博,361570,GSK-3β Inhibitor XXVII - Calbiochem

  • merck millipore,默克密理博,361570,GSK-3β Inhibitor XXVII - Calbiochem

    产品名称：GSK-3β Inhibitor XXVII - Calbiochem
    产品型号：361570
    The GSK-3β Inhibitor XXVII controls the biological activity of GSK-3β. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

    merck millipore,默克密理博,361570,GSK-3β Inhibitor XXVII - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,361570,GSK-3β Inhibitor XXVII - Calbiochem

    重要规格表

    经验配方
    C₂₁H₂₃N₇O₃S• 2.5 HCl•5H₂O
    描述
    概述 A cell-permeable pyridinylpyrazinecarboxamide compound that acts as a highly potent, reversible, and ATP-competitive inhibitor of GSK-3β (Ki = 4.9 nM) with ~110-fold greater selectivity over Cdk2 (Ki = 540 nM). Shows only a trivial effect on the activities of 26-related kinases at much higher doses. Blocks GSK-3β-mediated phosphorylation of Ser396 in stably transfected 3T3 fibroblasts expressing four-repeat tau protein (IC50 = 76 nM). Readily crosses blood-brain barrier and exhibits desirable bioavailability and aqueous solubility.
    产品目录编号 361570
    品牌系列 Calbiochem®
    同义词 3-Amino-6-(4-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-N-(pyridin-3-yl)pyrazine-2-carboxamide, HCl
    参考
    参考 Berg. S., et al. 2012. J. Med. Chem. 55, 9107.
    产品信息
    形式 Yellow powder
    Hill配方 C₂₁H₂₃N₇O₃S• 2.5 HCl•5H₂O
    化学配方 C₂₁H₂₃N₇O₃S• 2.5 HCl•5H₂O
    Molar Mass 634.8
    吸湿 Hygroscopic
    可逆 Y
    结构配方图像
    生物信息
    主靶 GSK-3β
    纯度 ≥99% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,361570,GSK-3β Inhibitor XXVII - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,OP80,Anti-APC (Ab-7) Mouse mAb (CC-1)
下一件merck millipore产品：merck millipore,默克密理博,HPTP2MAG-66K,MILLIPLEX MAP Human Pituitary Magnetic Bead Panel 2 - Endocrine Multiplex Assay


相关产品

merck millipore,默克密理博,MAB4084Z,Anti-AFP Receptor Antibody, azide free, clone 167H.1 merck millipore,默克密理博,MAB4084Z,Anti-AFP Receptor Antibody, azide free, clone 167H.1

merck millipore,默克密理博,AB16528,Anti-NIK Antibody, CT merck millipore,默克密理博,AB16528,Anti-NIK Antibody, CT

merck millipore,默克密理博,ABC25,Anti-Atg16L1 Antibody merck millipore,默克密理博,ABC25,Anti-Atg16L1 Antibody

merck millipore,默克密理博,ABC260,Anti-GSTM5 Antibody merck millipore,默克密理博,ABC260,Anti-GSTM5 Antibody

merck millipore,默克密理博,OP80,Anti-APC (Ab-7) Mouse mAb (CC-1) merck millipore,默克密理博,OP80,Anti-APC (Ab-7) Mouse mAb (CC-1)

merck millipore,默克密理博,HPTP2MAG-66K,MILLIPLEX MAP Human Pituitary Magnetic Bead Panel 2 - Endocrine Multiplex Assay merck millipore,默克密理博,HPTP2MAG-66K,MILLIPLEX MAP Human Pituitary Magnetic Bead Panel 2 - Endocrine Mult...

merck millipore,默克密理博,MAB2515,Anti-Collagen Type III Antibody, clone 3G4 merck millipore,默克密理博,MAB2515,Anti-Collagen Type III Antibody, clone 3G4

merck millipore,默克密理博,238470,Cremophor EL, Sterilized - CAS 61791-12-6 - Calbiochem merck millipore,默克密理博,238470,Cremophor EL, Sterilized - CAS 61791-12-6 - Calbiochem

merck millipore,默克密理博,SF-1267,TREM2; Human, Cyanine 5 RNA Detection Probe,SmartFlare merck millipore,默克密理博,SF-1267,TREM2; Human, Cyanine 5 RNA Detection Probe,SmartFlare

merck millipore,默克密理博,CBL171,Anti-Actin Antibody, smooth muscle, clone ASM-1 merck millipore,默克密理博,CBL171,Anti-Actin Antibody, smooth muscle, clone ASM-1


whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部