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merck millipore,默克密理博,36-010,Anti-phospho-MKK7/SKK4 (Thr275/Ser277) Antibody
产品名称：Anti-phospho-MKK7/SKK4 (Thr275/Ser277) Antibody
产品型号：36-010
Anti-phospho-MKK7/SKK4 (Thr275/Ser277) Antibody detects level of phospho-MKK7/SKK4 (Thr275/Ser277) & has been published & validated for use in WB.
merck millipore,默克密理博,36-010,Anti-phospho-MKK7/SKK4 (Thr275/Ser277) Antibody
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重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 36-010 品牌系列 Upstate
商名 - Upstate
描述 Anti-phospho-MKK7/SKK4 (Thr275/Ser277) Antibody 产品信息 格式 Affinity Purified 演示 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%. 应用 应用 Anti-phospho-MKK7/SKK4 (Thr275/Ser277) Antibody detects level of phospho-MKK7/SKK4 (Thr275/Ser277) & has been published & validated for use in WB. 主要应用 - Western Blotting
生物信息 免疫原品种 peptide corresponding to amino acids surrounding Thr275/Ser277 of human MKK7/SKK4. 宿主 Rabbit 特异性 MKK7/SKK4 同种型 IgG 品种反应性 Human Species Reactivity Note Cross-reactivity with mouse expected due to sequence homology. 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_145185.2
Entrez基因汇总 The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined. 基因符号 - Jnkk2
- MAP2K7
- MKK7
- PRKMK7
- MEK7
- MAPKK7
- JNKK2
修改 - Phosphorylation
纯化方法 Immunoaffinity purified UniProt编号 - O14733
UniProt汇总 FUNCTION: SwissProt: O14733 # Stress activated, dual specificity kinase that activates the JUN kinases MAPK8/JNK1, MAPK9/JNK2 and MAPK10/JNK3.
COFACTOR: Magnesium.
SIZE: 419 amino acids; 47485 Da
SUBCELLULAR LOCATION: Nucleus. Cytoplasm (By similarity).
TISSUE SPECIFICITY: Ubiquitous; with highest level of expression in skeletal muscle. Isoform 3 is found at low levels in placenta, fetal liver, and skeletal muscle.
PTM: Activated by phosphorylation on Ser/Thr.
SIMILARITY: SwissProt: O14733 ## Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily. & Contains 1 protein kinase domain.产品使用声明 质量保证 Routinely evaluated by immunoblot on detected recombinant MKK7b1 (14-542) that had been phosphorylated by MEKK1 (14-196). 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 1 year at -20°C 包装信息 数量 100 µL
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