merck millipore,默克密理愽
  • merck millipore,默克密理博,36-007,Anti-phospho-PRAK (Thr182) Antibody

  • merck millipore,默克密理博,36-007,Anti-phospho-PRAK (Thr182) Antibody

    产品名称：Anti-phospho-PRAK (Thr182) Antibody
    产品型号：36-007
    This Anti-phospho-PRAK (Thr182) Antibody is validated for use in WB for the detection of phospho-PRAK (Thr182).

    merck millipore,默克密理博,36-007,Anti-phospho-PRAK (Thr182) Antibody

  • 产品介绍
  • merck millipore,默克密理博,36-007,Anti-phospho-PRAK (Thr182) Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, H, MWBRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 36-007
    品牌系列 Upstate
    商名
    • Upstate
    描述 Anti-phospho-PRAK (Thr182) Antibody
    产品信息
    格式 Affinity Purified
    演示 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%.
    应用
    应用 This Anti-phospho-PRAK (Thr182) Antibody is validated for use in WB for the detection of phospho-PRAK (Thr182).
    主要应用
    • Western Blotting
    生物信息
    免疫原品种 peptide corresponding to amino acids surrounding phosphorylated Thr182 of human PRAK.
    宿主 Rabbit
    特异性 phosphorylated PRAK
    同种型 IgG
    品种反应性 RatHumanMouse
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_139078.1
    • NM_003668.2
    Entrez基因汇总 The protein encoded by this gene is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported.
    基因符号
    • PRAK
    • MAPKAPK5
    修改
    • Phosphorylation
    纯化方法 Immunoaffinity purified
    UniProt编号
    • Q8IW41
    UniProt汇总 FUNCTION: SwissProt: Q8IW41 # Mediates stress-induced small heat shock protein 27 phosphorylation.
    SIZE: 473 amino acids; 54220 Da
    SUBUNIT: Interacts with SQSTM1.
    SUBCELLULAR LOCATION: Cytoplasm (Probable). Nucleus. Note=Also observed in the nucleus.
    TISSUE SPECIFICITY: Expressed ubiquitously.
    PTM: Phosphorylated on Thr-182; which is the regulatory phosphorylation site and is located on the T-loop/loop 12.
    SIMILARITY: SwissProt: Q8IW41 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. & Contains 1 protein kinase domain.
    产品使用声明
    质量保证 routinely evaluated by immunoblot detected phosphorylated recombinant PRAK. Detection of PRAK is abolished after treatment with lambda phosphatase.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 2 years at -20°C
    包装信息
    数量 200 µg

    merck millipore,默克密理博,36-007,Anti-phospho-PRAK (Thr182) Antibody

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