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merck millipore,默克密理博,344510,FTase Inhibitor I - Calbiochem
产品名称：FTase Inhibitor I - Calbiochem
产品型号：344510
The FTase Inhibitor I controls the biological activity of FTase. This small molecule/inhibitor is primarily used for Cancer applications.
merck millipore,默克密理博,344510,FTase Inhibitor I - Calbiochem
- 产品介绍
重要规格表
经验配方 C₂₂H₃₈N₄O₃S₂ 描述 概述 A potent, cell-permeable, selective, peptidomimetic inhibitor of farnesyltransferase (FTase) that is approximately 37-fold more active against FTase (IC50 = 21 nM in vitro) than against geranylgeranyltransferase (GGTase; IC50 = 790 nM). Very resistant to proteolysis. 产品目录编号 344510 品牌系列 Calbiochem®
同义词 N-[2(S)-[2(R)-Amino-3-mercaptopropylamino]-3-methylbutyl]-Phe-Met-OH, B581 参考 参考 Yamaguchi, M., et al. 2004. Stroke 35, 1750.
Cox, A.D., et al. 1994. J. Biol. Chem. 269, 19203.
Garcia, A.M., et al. 1993. J. Biol. Chem. 268, 18415.产品信息 具有ATP竞争性 N 形式 White solid 配方 Supplied as a trifluoroacetate salt. Hill配方 C₂₂H₃₈N₄O₃S₂ 化学配方 C₂₂H₃₈N₄O₃S₂ Molar Mass 470.7 吸湿 Hygroscopic
可逆 N 结构配方图像 生物信息 主靶 FTase 主靶IC50 21 nM against FTase in vitro 纯度 ≥90% by HPLC 理化信息 细胞可渗透 Y 溶解度 DMSO or H₂O 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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