merck millipore,默克密理愽
  • merck millipore,默克密理博,344220,Formyl Peptide Receptor-Like 1 Antagonist, WRW⁴ - Calbiochem

  • merck millipore,默克密理博,344220,Formyl Peptide Receptor-Like 1 Antagonist, WRW⁴ - Calbiochem

    产品名称：Formyl Peptide Receptor-Like 1 Antagonist, WRW⁴ - Calbiochem
    产品型号：344220
    The Formyl Peptide Receptor-Like 1 Antagonist, WRW⁴ controls the biological activity of Formyl Peptide Receptor-Like 1.

    merck millipore,默克密理博,344220,Formyl Peptide Receptor-Like 1 Antagonist, WRW⁴ - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,344220,Formyl Peptide Receptor-Like 1 Antagonist, WRW⁴ - Calbiochem

    重要规格表

    经验配方
    C₆₁H₆₅N₁₅O₆
    描述
    概述 A Trp-rich hexapeptide that acts as a potent and specific antagonist of Formyl Peptide Receptor-Like 1 (FPRL1)-mediated signaling. Shown to bind to FPRL1 and interfere with the ligand-receptor interaction {IC50 = 230 nM for FPRL1 Agonist, WKYMVm (Cat. No. 344216)}. Completely blocks the ligand activated [Ca2+]i increase, ERK activation and chemotactic migration of FPRL1-expressing RBL-2H3 cells at 10 µM. Further, inhibits Aβ42 peptide-induced superoxide generation and prevents its internalization in human macrophages.
    产品目录编号 344220
    品牌系列 Calbiochem®
    同义词 H₂N-WRWWWW-CONH₂, FPRL1 Antagonist, WRW⁴
    参考
    参考 Bae, Y.S., et al. 2004. J. Immunol. 173, 607.
    产品信息
    具有ATP竞争性 N
    形式 White lyophilized solid
    配方 Supplied as a trifluoroacetate salt.
    Hill配方 C₆₁H₆₅N₁₅O₆
    化学配方 C₆₁H₆₅N₁₅O₆
    Molar Mass 1104.3
    吸湿 Hygroscopic
    肽序列 H-Trp-Arg-Trp-Trp-Trp-Trp-CONH₂
    可逆 N
    生物信息
    主靶 Formyl Peptide Receptor-Like 1 (FPRL1)
    主靶IC50 230 nM for FPRL1 Agonist
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 DMSO
    肽序列 H-Trp-Arg-Trp-Trp-Trp-Trp-CONH₂
    储存和货运信息
    货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
    毒性 Standard Handling
    储存 +2°C to +8°C
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,344220,Formyl Peptide Receptor-Like 1 Antagonist, WRW⁴ - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,239900,Cypermethrin - CAS 52315-07-8 - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,CB1039,Anti-S100A4 Mouse mAb (1F12-1G7)


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