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merck millipore,默克密理博,FCMAB322PE,Milli-Mark™ Anti-alpha-Tubulin-PE Antibody, clone DM1A
产品名称：Milli-Mark™ Anti-alpha-Tubulin-PE Antibody, clone DM1A
产品型号：FCMAB322PE
Detect alpha-Tubulin using this Milli-Mark Anti-alpha-Tubulin-PE Antibody, clone DM1A validated for use in FC.
merck millipore,默克密理博,FCMAB322PE,Milli-Mark™ Anti-alpha-Tubulin-PE Antibody, clone DM1A
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H FC M Phycoerythrin Monoclonal Antibody 描述 产品目录编号 FCMAB322PE 商名 - Milli-Mark
描述 Milli-Mark™ Anti-alpha-Tubulin-PE Antibody, clone DM1A Alternate Names - tubulin, alpha, brain-specific
- tubulin, alpha 3
- tubulin, alpha 1a
- Tubulin alpha-3 chain
- Tubulin B-alpha-1
- Alpha-tubulin 3
背景信息 Microtubules are involved in a wide variety of cellular activities ranging from mitosis and transport events to cell movement and the maintenance of cell shape. Tubulin itself is a globular protein which consists of two polypeptides (alpha and beta tubulin). Alpha and beta tubulin dimers are assembled to 13 protofilaments that form a microtubule of 22 nm diameter. Tyrosine ligase adds a C-terminal tyrosine to monomeric alpha tubulin. Assembled microtubules can again be detyrosinated by a cytoskeleton associated carboxypeptidase. Detyrosinated alpha tubulin is referred to as Glu-tubulin. Another post-translational modification of detyrosinated alpha tubulin is C-terminal polyglutamylation which is characteristic for microtubules in neuronal cells and the mitotic spindle. 产品信息 格式 Phycoerythrin 控制 - A431 cells.
演示 Purified mouse monoclonal IgG1 conjugated to PE in PBS with 0.1% sodium azide and 15 mg/mL BSA. 应用 应用 Detect alpha-Tubulin using this Milli-Mark Anti-alpha-Tubulin-PE Antibody, clone DM1A validated for use in FC. 主要应用 - Flow Cytometry
生物信息 免疫原品种 Purified human brain α-Tubulin. 克隆 DM1A 宿主 Mouse 特异性 This antibody recognizes α-Tubulin. 同种型 IgG1 品种反应性 Human Species Reactivity Note Tested and passed on Human. Unconjugated version (Cat. No.05-829) has predicted to work on Mouse, Pig, Bovine, Avian, Guinea pig, and Rat. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_006000
Entrez基因汇总 Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to mouse and rat Tuba1 gene. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q. 基因符号 - hum-a-tub1
- TUBA1A
- hum-a-tub2
- FLJ25113
- B-ALPHA-1
- TUBA3
纯化方法 Protein G Purified UniProt编号 - Q71U36
UniProt汇总 FUNCTION: SwissProt: Q71U36 # Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.
SIZE: 451 amino acids; 50136 Da
SUBUNIT: Dimer of alpha and beta chains.
PTM: Undergoes a tyrosination/detyrosination cycle, the cyclic removal and re-addition of a C-terminal tyrosine residue by the enzymes tubulin tyrosine carboxypeptidase (TTCP) and tubulin tyrosine ligase (TTL), respectively (By similarity).
SIMILARITY: SwissProt: Q71U36 ## Belongs to the tubulin family.产品使用声明 质量保证 Evaluated by flow cytometry using A431 cells. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt. 包装信息 数量 100 tests
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下一件merck millipore产品：merck millipore,默克密理博,239900,Cypermethrin - CAS 52315-07-8 - Calbiochem
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