• merck millipore,默克密理博,264158,Caspase Modulator II, 1541B - Calbiochem
  • merck millipore,默克密理博,264158,Caspase Modulator II, 1541B - Calbiochem

    产品名称:Caspase Modulator II, 1541B - Calbiochem
    产品型号:264158
    Caspase Modulator II, 1541B primarily used in Inhibition.

    merck millipore,默克密理博,264158,Caspase Modulator II, 1541B - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,264158,Caspase Modulator II, 1541B - Calbiochem

    重要规格表

    经验配方
    C₂₃H₁₅N₃O₄
    描述
    概述 A cell-permeable, of 8-Hydroxy analog 1541 (Cat. No. 529662) that is shown to selectively activate procaspase-3 (EC50 = 1.3 µM), but not procaspase-6. Both 1541 and 1541B are shown to effectively induce apoptosis in various cancer cell lines with comparable potencies, indicating that caspase-3 activation alone is as effective in cell death induction as simultaneous activations of caspase-3/-6 among cells tested. 1541B is expected to inhibit the activity of mature/active caspase-3 and exhibit reduced procaspase-3 activation at high concentrations.
    产品目录编号 264158
    品牌系列 Calbiochem®
    同义词 Procaspase-3 Activator III, 8-Hydroxy-2-oxo-2H-chromene-3-carboxylic acid-(3-imidazo[1,2-a]pyridin-2-yl-phenyl)-amide, Caspase-3 Inhibitor XVI
    参考
    参考 Wolan, D.W., et al. 2009. Science 326, 853.
    产品信息
    形式 Pale yellow solid
    Hill配方 C₂₃H₁₅N₃O₄
    化学配方 C₂₃H₁₅N₃O₄
    Molar Mass 397.4
    结构配方图像
    生物信息
    纯度 ≥95% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,264158,Caspase Modulator II, 1541B - Calbiochem

上一件merck millipore产品:merck millipore,默克密理博,CB1039,Anti-S100A4 Mouse mAb (1F12-1G7)
下一件merck millipore产品:merck millipore,默克密理博,219002,Caspase-3 Inhibitor V - Calbiochem



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