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merck millipore,默克密理博,344095,Fluvastatin, Sodium Salt - CAS 93957-55-2 - Calbiochem
产品名称：Fluvastatin, Sodium Salt - CAS 93957-55-2 - Calbiochem
产品型号：344095
A synthetic HMG-CoA reductase inhibitor (IC₅₀ = 40-100 nM for human liver microsomes) that acts as an anti-hypercholesterolemic agent.
merck millipore,默克密理博,344095,Fluvastatin, Sodium Salt - CAS 93957-55-2 - Calbiochem
- 产品介绍
重要规格表
经验配方 CAS号 C₂₄H₂₅FNNaO₄ 93957-55-2 描述 概述 A synthetic HMG-CoA reductase inhibitor (IC50 = 40-100 nM for human liver microsomes) that acts as an anti-hypercholesterolemic agent. Decreases the basal MMP-1 levels in culture media of endothelial cells in a time- and dose-dependent manner. Inhibits the formation of TBA-reactive substances in Fe(II)-supported peroxidation of liposomes (IC50 = 12 µM). Also available as a 10 mM solution in H2O(Cat. No. 344096). 产品目录编号 344095 品牌系列 Calbiochem®
同义词 (±)-(3Rʹ,5Sʹ,6E)-7-[3-(4-Fluorophenyl)-1-isopropylindol-2-yl]-3,5-dihydroxy-6-heptenoate, sodium 参考 参考 Yamamoto, A., et al. 2001. J. Pharm. Pharmacol. 53, 227.
Dansette, P.M., et al. 2000. Exp. Toxicol. Pathol. 52, 145.
Ikeda, U., et al. 2000. Hypertension 36, 325.
Levy, R.I., et al. 1993. Circulation 87 (4 Suppl.), III45.
Tse, F.L.S. et al. 1992. J. Clin. Pharmacol. 32, 630.
Yuan, J., et al. 1991. Atherosclerosis 87, 147.产品信息 CAS号 93957-55-2 具有ATP竞争性 N 形式 Light yellow solid Hill配方 C₂₄H₂₅FNNaO₄ 化学配方 C₂₄H₂₅FNNaO₄ Molar Mass 433.4 可逆 N 结构配方图像 生物信息 主靶 HMG-CoA reductase 主靶IC50 40-100 nM against HMG-CoA reductase in human liver microsomes 纯度 ≥98% by HPLC 理化信息 细胞可渗透 N 溶解度 H₂O, DMSO, or MeOH GHS安全信息 RTECS MJ9675050 安全信息 R相 R: 62-63
Possible risk of impaired fertility.
Possible risk of harm to the unborn child.S相 S: 22-24/25-36/37/39-45
Do not breathe dust.
Avoid contact with skin and eyes.
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).储存和货运信息 货运代码 Ambient Temperature Only
毒性 Carcinogenic / Teratogenic
储存 -20°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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