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品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Purified Polyclonal Antibody 描述 产品目录编号 07-735 品牌系列 Upstate
商名 - Upstate
描述 Anti-CENP-B Antibody 产品信息 格式 Purified 应用 应用 Anti-CENP-B Antibody is a Rabbit Polyclonal Antibody for detection of CENP-B also known as Centromere autoantigen B & has been tested in WB. 主要应用 - Western Blotting
生物信息 免疫原品种 Beta galactosidase fusion protein of human CENP-B. 宿主 Rabbit 特异性 Beta galactosidase fusion protein of human CENP-B. 同种型 IgG 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_001810.5
Entrez基因汇总 This gene product is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. The DNA binding domain recognizes and binds a 17-bp sequence (CENP-B box) in the centromeric alpha satellite DNA. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies. 基因符号 - CENP-B
- CENPB
纯化方法 Protein A purfied UniProt编号 - P07199
UniProt汇总 FUNCTION: SwissProt: P07199 # Interacts with centromeric heterochromatin in chromosomes and binds to a specific subset of alphoid satellite DNA, called the CENP-B box. May organize arrays of centromere satellite DNA into a higher order structure which then directs centromere formation and kinetochore assembly in mammalian chromosomes.
SIZE: 599 amino acids; 65171 Da
SUBUNIT: Homodimer.
SUBCELLULAR LOCATION: Nucleus.
SIMILARITY: SwissProt: P07199 ## Contains 1 HTH CENPB-type DNA-binding domain. & Contains 1 HTH psq-type DNA-binding domain.产品使用声明 质量保证 Routinely evaluated by immunoblot. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C from date of shipment 包装信息 数量 100 µg
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