merck millipore,默克密理愽
  • merck millipore,默克密理博,AB15076,Anti-Ephrin Receptor B2 Antibody

  • merck millipore,默克密理博,AB15076,Anti-Ephrin Receptor B2 Antibody

    产品名称：Anti-Ephrin Receptor B2 Antibody
    产品型号：AB15076
    Anti-Ephrin Receptor B2 Antibody detects level of Ephrin Receptor B2 & has been published & validated for use in WB.

    merck millipore,默克密理博,AB15076,Anti-Ephrin Receptor B2 Antibody

  • 产品介绍
  • merck millipore,默克密理博,AB15076,Anti-Ephrin Receptor B2 Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    RWBRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 AB15076
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Ephrin Receptor B2 Antibody
    产品信息
    格式 Affinity Purified
    演示 Liquid in PBS with 0.1% sodium azide.
    应用
    应用 Anti-Ephrin Receptor B2 Antibody detects level of Ephrin Receptor B2 & has been published & validated for use in WB.
    主要应用
    • Western Blotting
    应用说明 Western blot: 1:500-1:2,000 on adult rat brain lysate.

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 Synthetic peptide.
    宿主 Rabbit
    特异性 Ephrin Receptor B2. By Western blot the antibody recognizes a doublet band at ~90-118 kDa in adult rat brain lysate.
    品种反应性 Rat
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_017449.3
    • NM_004442.6
    Entrez基因汇总 Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members.
    基因符号
    • Tyro5
    • EPHB2
    • EphB2
    • CAPB
    • EPHT3
    • Hek5
    • DRT
    • EPTH3
    • TYRO5
    • ERK
    • HEK5
    • MGC87492
    • PCBC
    纯化方法 Immunoaffinity purified
    UniProt编号
    • P29323
    UniProt汇总 FUNCTION: SwissProt: P29323 # Receptor for members of the ephrin-B family. Acts as a tumor suppressor.
    SIZE: 1055 amino acids; 117493 Da
    SUBUNIT: The ligand-activated form interacts with multiple proteins, including GTPase-activating protein (RASGAP) through its SH2 domain. Binds RASGAP through the juxtamembrane tyrosines residues. Interacts with PRKCABP and GRIP1 (By similarity).
    SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
    TISSUE SPECIFICITY: Brain, heart, lung, kidney, placenta, pancreas, liver and skeletal muscle. Preferentially expressed in fetal brain.
    DISEASE:SwissProt: P29323 # Defects in EPHB2 are involved in the progression of prostate cancer [MIM:176807]. & Defects in EPHB2 are involved in the development of prostate cancer metastasis to the brain [MIM:603688].
    SIMILARITY: SwissProt: P29323 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily. & Contains 2 fibronectin type-III domains. & Contains 1 protein kinase domain. & Contains 1 SAM (sterile alpha motif) domain.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,AB15076,Anti-Ephrin Receptor B2 Antibody

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