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merck millipore,默克密理博,344085,Folimycin, Streptomyces sp. - CAS 80890-47-7 - Calbiochem
产品名称:Folimycin, Streptomyces sp. - CAS 80890-47-7 - Calbiochem
产品型号:344085
A highly sensitive and specific inhibitor of vacuolar-type H+-ATPase (V-type; Ki = 20 pM).
merck millipore,默克密理博,344085,Folimycin, Streptomyces sp. - CAS 80890-47-7 - Calbiochem
- 产品介绍
重要规格表
经验配方 CAS号 C₄₆H₇₅NO₁₄ 80890-47-7 描述 概述 A highly sensitive and specific inhibitor of vacuolar-type H+-ATPase (V-type; Ki = 20 pM). Inhibits acidification of organelles, such as lysosomes and the Golgi apparatus. Also blocks cell surface expression of viral envelope glycoproteins without affecting their synthesis. Useful for studies of intracellular protein translocation. Exhibits cytotoxic effects on a number of cell lines in a cell viability assay. 产品目录编号 344085 品牌系列 Calbiochem®
同义词 Concanamycin A 参考 参考 Kane, M.D., et al. 1999. J. Neurochem. 72, 1939.
Nishihara, T., et al. 1995. Biochem. Biophys. Res. Commun. 212, 255.
Muroi, M., et al. 1994. Biosci. Biotech. Biochem. 58, 425.
Drose, S., et al. 1993. Biochemistry 32, 3902.
Muroi, M., et al. 1993. Biochem. Biophys. Res. Commun. 193, 999.
Muroi, M., et al. 1993. Cell Struct. Funct. 18, 139.产品信息 CAS号 80890-47-7 具有ATP竞争性 N 形式 Lyophilized solid Hill配方 C₄₆H₇₅NO₁₄ 化学配方 C₄₆H₇₅NO₁₄ Molar Mass 866.1 可逆 N 结构配方图像 生物信息 主靶 Vacuolar-type H+-ATPase 主靶Ki 20 pM against vacuolar-type H+-ATPase 纯度 ≥90% by HPLC 理化信息 细胞可渗透 N 溶解度 DMSO GHS安全信息 RTECS LP5970000 安全信息 R相 R: 28-37
Very toxic if swallowed.
Irritating to respiratory system.S相 S: 36/37/39-45
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).储存和货运信息 货运代码 Ambient Temperature Only
毒性 Highly Toxic
有害材料注意事项: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
储存 -20°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 year at -20°C.
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