merck millipore,默克密理愽
  • merck millipore,默克密理博,341251,Fascaplysin, Synthetic - CAS 114719-57-2 - Calbiochem

  • merck millipore,默克密理博,341251,Fascaplysin, Synthetic - CAS 114719-57-2 - Calbiochem

    产品名称：Fascaplysin, Synthetic - CAS 114719-57-2 - Calbiochem
    产品型号：341251
    A cell-permeable red pigment, originally isolated from marine sponge, that acts as a potent, ATP-competitive inhibitor of Cdk4/D1 (IC₅₀ = 0.35 µM).

    merck millipore,默克密理博,341251,Fascaplysin, Synthetic - CAS 114719-57-2 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,341251,Fascaplysin, Synthetic - CAS 114719-57-2 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₈H₁₁ClN₂O114719-57-2
    描述
    概述 A cell-permeable red pigment, originally isolated from marine sponge, that acts as a potent, ATP-competitive inhibitor of Cdk4/D1 (IC50 = 0.35 µM). It inhibits Cdk6/D1 with much lower potency (IC50 = 3.4 µM) and has been shown not to affect the activities of several other Cdk’s (IC50 > 20 µM) and tyrosine kinases (IC50 > 10 µM). Part of its biological effects may also be attributed to its ability to intercalate into DNA. Has also been shown to display anti-microbial activity.
    产品目录编号 341251
    品牌系列 Calbiochem®
    参考
    参考 Hormann, A., et al. 2001. Bioorg. Med. Chem. 9, 917.
    Kirsch, G., et al. 2000. J. Nat. Prod. 63, 825.
    Soni, R., et al. 2000. Biochem. Biophys. Res. Commun. 275, 877.
    产品信息
    CAS号 114719-57-2
    具有ATP竞争性 Y
    形式 Brown solid
    Hill配方 C₁₈H₁₁ClN₂O
    化学配方 C₁₈H₁₁ClN₂O
    Molar Mass 306.8
    吸湿 Hygroscopic
    可逆 Y
    结构配方图像
    生物信息
    主靶 CDK4/D1
    主靶IC50 0.35 µM against Cdk4/D1
    纯度 ≥98% by NMR
    理化信息
    细胞可渗透 Y
    溶解度 DMSO or MeOH
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Toxic
    有害材料注意事项： Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
    储存 +2°C to +8°C
    避光 Protect from light
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,341251,Fascaplysin, Synthetic - CAS 114719-57-2 - Calbiochem

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