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merck millipore,默克密理博,33-038,PI 3-Kinase Class II HTRF Assay
产品名称：PI 3-Kinase Class II HTRF Assay
产品型号：33-038
One-plate kit (384 wells) of reagents for performing PI 3-Kinase (Class II) 4-step HTRF assays. Suitable for the following Kinases: PI3KC2α, PI3KC2β & PI3KC2γ.
merck millipore,默克密理博,33-038,PI 3-Kinase Class II HTRF Assay
- 产品介绍
描述 产品目录编号 33-038 品牌系列 Upstate
商名 - Upstate
- HTRF
描述 PI 3-Kinase Class II HTRF Assay 产品信息 部件 - Stop Reagent C
- Reaction Buffer (4X)
- DM A Detection Reagent
- DM C Detection Reagent
- DM D Detection Reagent
- Phosphatidylinositol (1mM)
- Phosphatidylserine (1mM)
检测方法 HTRF 应用 应用 One-plate kit (384 wells) of reagents for performing PI 3-Kinase (Class II) 4-step HTRF assays. Suitable for the following Kinases: PI3KC2α, PI3KC2β & PI3KC2γ. 主要应用 - Kinase Assay
生物信息 品种反应性 MouseHuman 可用的分析物 - PI 3-Kinase Class II
Entrez基因编号 - NM_004570.4
- NM_002645.2
- NM_002646.3
Entrez基因汇总 Phosphoinositide 3-kinase-C2 proteins generate phosphatidylinositol 3-phosphate (PtdIns3P) and phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) that act as second messengers. This protein belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is sensitive to low nanomolar levels of the inhibitor wortmanin. The C2 domain of this protein was shown to bind phospholipids but not Ca2+, which suggests that this enzyme may function in a calcium-independent manner. 基因符号 - PI3KC2γ
- PI3KC2α
- PI3KC2β
靶子系列 PI3K/PI4K 产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 12 months at -70°C 包装信息 数量 384 wells 包装 Kit capacity: 384 wells
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