• merck millipore,默克密理博,324516,eEF2K Inhibitor, A-484954 - CAS 142557-61-7 - Calbiochem
  • merck millipore,默克密理博,324516,eEF2K Inhibitor, A-484954 - CAS 142557-61-7 - Calbiochem

    产品名称:eEF2K Inhibitor, A-484954 - CAS 142557-61-7 - Calbiochem
    产品型号:324516
    The eEF2K Inhibitor, A-484954, also referenced under CAS 142557-61-7, controls the biological activity of eEF2K Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphor More>>

    merck millipore,默克密理博,324516,eEF2K Inhibitor, A-484954 - CAS 142557-61-7 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,324516,eEF2K Inhibitor, A-484954 - CAS 142557-61-7 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₃H₁₅N₅O₃142557-61-7
    描述
    概述 A cell-permeable pyrido-pyrimidinedione derivative that acts as a highly potent and selective inhibitor of eukaryotic elongation factor-2 kinase (eEF2K) (IC50= 280 nM). Exhibits very little activity against a broad panel of serine/threonine and protein tyrosine kinases. Inhibits eEF2 phosphorylation in multiple cell lines tested without affecting the net eEF2 levels. At concentration where it inhibits eEF2K activity, it has no effect on the proliferation of cancer cell lines.
    产品目录编号 324516
    品牌系列 Calbiochem®
    同义词 7-amino-1-cyclopropyl-3-ethyl-2,4-dioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-6-carboxamide, Eukaryotic elongation factor-2 kinase inhibitor, A-484954
    参考
    参考 Chen, Z., et al. 2011. J. Bio. Chem. 286, 43951.
    产品信息
    CAS号 142557-61-7
    形式 Off-white powder
    Hill配方 C₁₃H₁₅N₅O₃
    化学配方 C₁₃H₁₅N₅O₃
    Molar Mass 289.3
    结构配方图像
    生物信息
    纯度 ≥98% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,324516,eEF2K Inhibitor, A-484954 - CAS 142557-61-7 - Calbiochem

上一件merck millipore产品:merck millipore,默克密理博,391333,HEPES, Sodium Salt, ULTROL Grade - CAS 75277-39-3 - Calbiochem
下一件merck millipore产品:merck millipore,默克密理博,233490,Coagulation Factor XII, Human Plasma



whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部