merck millipore,默克密理愽
  • merck millipore,默克密理博,324483,Ebselen - CAS 60940-34-3 - Calbiochem

  • merck millipore,默克密理博,324483,Ebselen - CAS 60940-34-3 - Calbiochem

    产品名称：Ebselen - CAS 60940-34-3 - Calbiochem
    产品型号：324483
    A cell-permeable, non-selective inhibitor of COX-1 and COX-2.

    merck millipore,默克密理博,324483,Ebselen - CAS 60940-34-3 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,324483,Ebselen - CAS 60940-34-3 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₃H₉NOSe60940-34-3
    描述
    概述 A cell-permeable, non-selective inhibitor of COX-1 and COX-2. An excellent scavenger of peroxynitrite. Glutathione peroxidase mimetic. Inhibits radiation-induced apoptosis in thymocytes by scavenging peroxides. A neuroprotective agent active against acute focal ischemic injury. Inhibits LPS-induced NF-κB nuclear translocation and LPS-induced phosphorylation of JNK.
    产品目录编号 324483
    品牌系列 Calbiochem®
    同义词 2-Phenyl-1,2-benzisoselenazol-3(2H)-one, PZ51
    参考
    参考 Shimohashi, N., et al. 2000. J. Cell Biochem. 78, 595.
    Ramakrishnan, N., et al. 1996. Biochem. Pharmacol. 51, 1443.
    Ullrich, V., et al. 1996. Biochem. Pharmacol. 52, 15.
    Dawson, D.A., et al. 1995. Neurosci. Lett. 185, 65.
    Wang, J.F., et al. 1992. Hepatology 5, 112.
    Maiorino, M., et al. 1988. Biochem. Pharmacol. 37, 2267.
    Parnham, M.J., and Graf, E. 1987. Biochem. Pharmacol. 36, 3095.
    Parnham, M.J., and Kindt, S. 1984. Biochem. Pharmacol. 33, 3247.
    产品信息
    CAS号 60940-34-3
    具有ATP竞争性 N
    形式 Lyophilized solid
    Hill配方 C₁₃H₉NOSe
    化学配方 C₁₃H₉NOSe
    Molar Mass 274.2
    可逆 N
    结构配方图像
    生物信息
    主靶 COX-1, COX-2
    纯度 ≥98% by TLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO or EtOH
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    无需冷冻 No
    特殊指南 Following reconstituion, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

    merck millipore,默克密理博,324483,Ebselen - CAS 60940-34-3 - Calbiochem

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