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描述 概述 Native coagulation factor Xa from human plasma prepared from homogeneous Factor X by activation with Russel’s viper venom. The venom is removed after activation. During coagulation, in the presence of Ca2+ and membrane phospholipids, a complex of Factor Xa and Factor Va (the prothrombinase complex) activates prothrombin to thrombin. Inhibitors include AEBSF (Cat. No. 101500), DFP (Cat. No. 30967), PMSF (Cat. No. 52332), and Soybean Trypsin Inhibitor (Cat. No. 650357). Sold on the basis of plasma equivalent units of Factor X. 100 plasma equivalent units are equal to 800 µg of Factor X. 产品目录编号 233526 品牌系列 Calbiochem®
参考 参考 Heeb, M.J., et al. 1994. Proc. Natl. Acad. Sci. USA 91, 2728.
Lindhout, T., et al. 1994. Biochem. J. 297, 131.
Morishita, H., et al. 1994. Thrombosis Res. 73, 193.
Lupu, C., et al. 1993. Thrombosis Haemostasis 70, 579.
Jordan, S.P., et al. 1992. Biochemistry 31, 5374.
Schoen, P., et al. 1992. Br. J. Haemotol. 81, 255.
Tracy, P.B., et al. 1992. Methods Enzymol. 215, 329.
Lawson, J.H., and Mann, K.G. 1991. J. Biol. Chem. 226, 11317.
Tans, G., et al. 1991. J. Biol. Chem. 266, 21864.
Owen, W.G., et al. 1974. J. Biol. Chem. 249, 594.产品信息 CAS号 9002-05-5 EC号 3.4.21.6 形式 Lyophilized 配方 Lyophilized from 700 mM NaCl, 20 mM Tris-HCl, pH 7.4. Molar Mass 46000 生物信息 纯度 homogeneous by SDS-PAGE 来源 Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV. 特异活性 ≥170 units/mg protein 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
无需冷冻 No
特殊指南 Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 6 months at 4°C.
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