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经验配方 CAS号 C₁₇H₂₂N₂O₃ · HCl 1188890-36-9 描述 概述 A selective inhibitor of MMP-13 (IC50 = 10 µM). Binds to the S1′ pocket of MMP-13 with its morpholine ring adjacent to the catalytic zinc atom. Does not inhibit MMP-1, MMP-9, and TACE. 产品目录编号 233105 品牌系列 Calbiochem®
参考 参考 Chen, J.M., et al. 2000. J. Am. Chem. Soc. 122, 9648. 产品信息 CAS号 1188890-36-9 具有ATP竞争性 N 形式 Light yellow solid Hill配方 C₁₇H₂₂N₂O₃ · HCl 化学配方 C₁₇H₂₂N₂O₃ · HCl Molar Mass 338.8 吸湿 Hygroscopic
可逆 N 结构配方图像 生物信息 主靶 MMP-13 主靶IC50 10 µM against MMP-13 纯度 ≥97% by HPLC 理化信息 细胞可渗透 N 溶解度 H₂O 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.
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