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重要规格表
主要应用 品种 级联部件 EA Human Substrate 描述 产品目录编号 23-034 品牌系列 Upstate
商名 - Upstate
描述 p53 Protein, 10 µg 长描述 N-terminal c-Myc, 6His-tagged, recombinant human p53 full length, expressed by baculovirus in Sf21 insect cells. Purified using immobilized metal affinity chromatography. Alternate Names - TP53
- Cellular tumour antigen p53
- Antigen NY-CO-13
- Phosphoprotein p53
- Tumour suppressor p53
背景信息 p53 is expressed in a wide variety of tissues and plays a major role in preventing tumour development. It is involved in cell cycle regulation, functioning as a trans-activator to negatively regulate cell division by controlling a set of genes required for this process. It acts as a tumour suppressor in many tumour types by stimulating either apoptosis or growth arrest depending on the physiological circumstances and the cell type. Defects in p53 expression have been implicated in several diseases including; choroid plexus papilloma, lung cancer, head/neck squamous cell carcinomas, oesophageal squamous cell carcinoma, Li-Fraumeni syndrome, and hereditary adrenocortical carcinoma. 应用 应用 Full length, recombinant human p53. N-terminal c-Myc, 6His-tagged. For use in Enzyme Assays. Functions as a substrate in ubiquitination assays. 主要应用 - Enzyme Assay
生物信息 品种 Human 特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. 级联部件 Substrate Entrez基因编号 - BC003596 (GenBank Number)
纯化方法 Purified using immobilized metal affinity chromatography. 产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
包装信息 数量 10 µg
上一件merck millipore产品：merck millipore,默克密理博,12668,Albumin, Human Serum, Fraction V
下一件merck millipore产品：merck millipore,默克密理博,116802,Adenosine 3ʹ,5ʹ-cyclic Monophosphate, N⁶-Benzoyl-, Sodium Salt - CAS 30275-80-0 - Calbiochem
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