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merck millipore,默克密理博,23-032M,MDM2/CK1δ Protein, active, 250 µg
产品名称:MDM2/CK1δ Protein, active, 250 µg
产品型号:23-032M
Active, full length, recombinant human MDM2 (N-terminal GST-tagged) combined in vitro with CK1δ, active. For use in Enzyme Assays. Functions as an E3 ligase in ubiquitination assays.
merck millipore,默克密理博,23-032M,MDM2/CK1δ Protein, active, 250 µg
- 产品介绍
重要规格表
主要应用 品种 级联部件 EA Human E3 描述 产品目录编号 23-032M 品牌系列 Upstate
商名 - Upstate
描述 MDM2/CK1δ Protein, active, 250 µg 长描述 N-terminal GST-tagged, recombinant human MDM2 full length, expressed in E.coli. Purified using glutathione sepharose followed by gel filtration. Combined in vitro with CK1δ, active (Item # 14-520) Alternate Names - Hdm2
- Double minute 2 protein
- p53-binding protein Mdm2
背景信息 MDM2 is an E3 ubiquitin ligase that regulates the turnover of several cellular factors including the p53 tumour suppressor protein and notably MDM2 itself. The suppression of p53 activity by an amplified Mdm2 gene has been observed in many tumours, including soft tissue sarcomas, osteosarcomas and breast tumours. 应用 应用 Active, full length, recombinant human MDM2 (N-terminal GST-tagged) combined in vitro with CK1δ, active. For use in Enzyme Assays. Functions as an E3 ligase in ubiquitination assays. 主要应用 - Enzyme Assay
生物信息 品种 Human 特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. 级联部件 E3 Entrez基因编号 - AF527840 (GenBank Number)
纯化方法 Purified using glutathione sepharose followed by gel filtration. 产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
包装信息 数量 250 µg
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