merck millipore,默克密理愽
  • merck millipore,默克密理博,219503,Cdk4 Inhibitor V - CAS 943746-57-4 - Calbiochem

  • merck millipore,默克密理博,219503,Cdk4 Inhibitor V - CAS 943746-57-4 - Calbiochem

    产品名称：Cdk4 Inhibitor V - CAS 943746-57-4 - Calbiochem
    产品型号：219503
    The Cdk4 Inhibitor V, also referenced under CAS 943746-57-4, controls the biological activity of Cdk4. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applicati More>>

    merck millipore,默克密理博,219503,Cdk4 Inhibitor V - CAS 943746-57-4 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,219503,Cdk4 Inhibitor V - CAS 943746-57-4 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₉H₁₈IN₃O₄943746-57-4
    描述
    概述 A cell-permeable and metabolically stable (t1/2 >30 min at 37 °C in rat liver microsomes stability assays) pyridinylmethylamino-isoquinoline dione that acts as a potent, ATP-binding site-targeting Cdk4/D1 inhibitor (IC50 = 30 nM) and an effective antiproliferative agent against HCT116 and MCF-7 cancer cells (IC50 = 0.73 and 0.88 µM, respectively), affecting Cdk2/E and Cdk1/B only at much higher concentrations (IC50 = 1.6 and 25.3 µM, respectively).
    产品目录编号 219503
    品牌系列 Calbiochem®
    同义词 4-(((4-Hydroxy-5-propoxy-pyridin-2-ylmethyl)-amino)-methylene)-6-iodo-4H-isoquinoline-1,3-dione
    参考
    参考 Tsou, H.R., et al. 2009. J. Med. Chem. 52, 2289.
    产品信息
    CAS号 943746-57-4
    形式 Caramel powder
    Hill配方 C₁₉H₁₈IN₃O₄
    化学配方 C₁₉H₁₈IN₃O₄
    Molar Mass 479.3
    结构配方图像
    生物信息
    纯度 ≥98% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
    毒性 Regulatory Review
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,219503,Cdk4 Inhibitor V - CAS 943746-57-4 - Calbiochem

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