merck millipore,默克密理愽
  • merck millipore,默克密理博,203715,BQ-610 - Calbiochem

  • merck millipore,默克密理博,203715,BQ-610 - Calbiochem

    产品名称：BQ-610 - Calbiochem
    产品型号：203715
    A highly selective ETA receptor antagonist (IC₅₀ = 20 nM) that attenuates ET-induced reduction in cardiac output.

    merck millipore,默克密理博,203715,BQ-610 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,203715,BQ-610 - Calbiochem

    重要规格表

    经验配方
    C₃₆H₄₇N₇O₆
    描述
    概述 A highly selective ETA receptor antagonist (IC50 = 20 nM) that attenuates ET-induced reduction in cardiac output. Also inhibits ET-1- and ET-3-induced activation of adenylate cyclase (IC50 = 28.2 nM). BQ-610 is 30-fold more potent than BQ-123 (Cat. No. 05-23-3831) in porcine aortic smooth muscle membrane assay.
    产品目录编号 203715
    品牌系列 Calbiochem®
    参考
    参考 Beyer, M.E., et al. 1999. Hypertension 33, 145.
    Carratu, P., et al. 1997. Am. J. Physiol. 272, L1021.
    Illing, B., et al. 1996. J. Cardiovasc. Pharmacol. 27, 487.
    Han, H., et al. 1995. J. Mol. Cell. Cardiol. 27, 761.
    Ishikawa, K., et al. 1992. in Peptides, Schneider and Eberle, eds. (ESCOM), p. 685.
    产品信息
    具有ATP竞争性 N
    形式 White lyophilized powder
    配方 Supplied as an ammonium salt.
    Hill配方 C₃₆H₄₇N₇O₆
    化学配方 C₃₆H₄₇N₇O₆
    Molar Mass 673.8
    吸湿 Hygroscopic
    肽序列 Homopiperidinyl-CO-Leu-D-Trp(CHO)-D-Trp-ONH4
    可逆 N
    生物信息
    主靶 ETA receptor antagonist
    主靶IC50 20 nM as ETA receptor antagonist that attenuates ET-induced reduction in cardiac output
    纯度 ≥90% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 H₂O
    肽序列 Homopiperidinyl-CO-Leu-D-Trp(CHO)-D-Trp-ONH4
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

    merck millipore,默克密理博,203715,BQ-610 - Calbiochem

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