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merck millipore,默克密理博,189484,Autocamtide-2 Related Inhibitory Peptide II - Calbiochem
产品名称：Autocamtide-2 Related Inhibitory Peptide II - Calbiochem
产品型号：189484
The Autocamtide-2 Related Inhibitory Peptide II controls the biological activity of calmodulin-dependent protein kinase II. This small molecule/inhibitor is primarily used for Phosphorylation & Dephos More>>
merck millipore,默克密理博,189484,Autocamtide-2 Related Inhibitory Peptide II - Calbiochem
- 产品介绍
重要规格表
经验配方 C₇₁H₁₂₃N₂₃O₁₉ 描述 概述 An AIP (Cat. No. 189480) analog, in which Ala3 and Val10 are replaced with Lys and Phe respectively. Acts as a highly specific, potent inhibitor of calmodulin-dependent protein kinase II (CaMKII; IC50 = 4.1 nM). Displays ~10-fold greater potency than AIP. Inhibits PKC at higher concentrations (IC50 = 1 µM) and does not affect the activities of CaMK IV and PKA (IC50 > 100 µM). 产品目录编号 189484 品牌系列 Calbiochem®
同义词 KKKLRRQEAFDAL, A3K/V10F-AIP, AIP-II 参考 参考 Ishida, A., et al. 1998. FEBS Lett. 427, 115. 产品信息 具有ATP竞争性 N 形式 White lyophilized solid 配方 Supplied as a trifluoroacetate salt. Hill配方 C₇₁H₁₂₃N₂₃O₁₉ 化学配方 C₇₁H₁₂₃N₂₃O₁₉ Molar Mass 1602.9 吸湿 Hygroscopic
肽序列 H-Lys-Lys-Lys-Leu-Arg-Arg-Gln-Glu-Ala-Phe-Asp-Ala-Leu-OH 可逆 N 生物信息 主靶 CAM Kinase-2 主靶IC50 4.1 nM 纯度 ≥97% by HPLC 理化信息 细胞可渗透 N 溶解度 DMSO 肽序列 H-Lys-Lys-Lys-Leu-Arg-Arg-Gln-Glu-Ala-Phe-Asp-Ala-Leu-OH 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 +2°C to +8°C
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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