merck millipore,默克密理愽
  • merck millipore,默克密理博,175580,Angiogenesis Inhibitor - CAS 186611-44-9 - Calbiochem

  • merck millipore,默克密理博,175580,Angiogenesis Inhibitor - CAS 186611-44-9 - Calbiochem

    产品名称：Angiogenesis Inhibitor - CAS 186611-44-9 - Calbiochem
    产品型号：175580
    The Angiogenesis Inhibitor, also referenced under CAS 186611-44-9, controls the biological activity of Angiogenesis. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphoryla More>>

    merck millipore,默克密理博,175580,Angiogenesis Inhibitor - CAS 186611-44-9 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,175580,Angiogenesis Inhibitor - CAS 186611-44-9 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₂H₉N₃O186611-44-9
    描述
    概述 A cell-permeable indolinone compound that displays anti-angiogenesis properties (30% inhibition of control at 10 µM in an in vitro rat aortic ring model ) with a potency that is comparable to that of SU5416 (Cat. No. 676487; 22% inhibition of control at 10 µM). Acts as a moderate ATP-competitive inhibitor of hEGF-R tyrosine kinase activity (54% inhibition at 10 µM).
    产品目录编号 175580
    品牌系列 Calbiochem®
    同义词 (Z,E)-3-(Imidazol-4-ylmethylene)indolin-2-one
    参考
    参考 Braud, E., et al. 2003. J. Enzyme Inhib. Med. Chem. 18, 243.
    产品信息
    CAS号 186611-44-9
    具有ATP竞争性 Y
    形式 Yellow solid
    Hill配方 C₁₂H₉N₃O
    化学配方 C₁₂H₉N₃O
    Molar Mass 211.2
    可逆 N
    结构配方图像
    生物信息
    主靶 hEGF-R tyrosine kinase activity
    主靶IC50 54% inhibition at 10 µM against hEGF-R tyrosine kinase activity
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Carcinogenic / Teratogenic
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,175580,Angiogenesis Inhibitor - CAS 186611-44-9 - Calbiochem

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