merck millipore,默克密理愽
  • merck millipore,默克密理博,654255,TNF-α Antagonist - Calbiochem

  • merck millipore,默克密理博,654255,TNF-α Antagonist - Calbiochem

    产品名称：TNF-α Antagonist - Calbiochem
    产品型号：654255
    The TNF-α Antagonist controls the biological activity of TNF-α.

    merck millipore,默克密理博,654255,TNF-α Antagonist - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,654255,TNF-α Antagonist - Calbiochem

    重要规格表

    经验配方
    C₅₈H₇₁N₁₁O₁₅S₂
    描述
    概述 An exocyclic peptidomimetic that acts as a TNF-α antagonist (IC50 = 5 µM) in the binding assay. Blocks TNF-α-mediated apoptosis in mouse L929 cells. The designation WP9QY arises from the binding to the site observed in the TNF-β/TNF-receptor (I) complex as template, and the introduction of amino acids Glu and Tyr.
    产品目录编号 654255
    品牌系列 Calbiochem®
    同义词 TNF Antagonist, WP9QY, Tumor Necrosis Factor Antagonist, TNF-TNFR Signaling Inhibitor I
    参考
    参考 Takasaki, W., et al. 1997. Nat. Biotechnol. 15, 1266.
    产品信息
    具有ATP竞争性 N
    声明 Sold under license of U.S. Patent 6,265,535.
    形式 Lyophilized
    配方 Supplied as a trifluoroacetate salt.
    Hill配方 C₅₈H₇₁N₁₁O₁₅S₂
    化学配方 C₅₈H₇₁N₁₁O₁₅S₂
    Molar Mass 1226.4
    吸湿 Hygroscopic
    肽序列 H-Tyr-Cys-Trp-Ser-Gln-Tyr-Leu-Cys-Tyr-OH (disulfide bond: 2 → 8)
    可逆 N
    生物信息
    主靶 TNF-α
    主靶IC50 5 µM as TNF-α antagonist
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 H₂O or 5% Acetic Acid
    肽序列 H-Tyr-Cys-Trp-Ser-Gln-Tyr-Leu-Cys-Tyr-OH (disulfide bond: 2 → 8)
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 1 month at -70°C.

    merck millipore,默克密理博,654255,TNF-α Antagonist - Calbiochem

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