merck millipore,默克密理愽
  • merck millipore,默克密理博,17-131,Src Assay Kit

  • merck millipore,默克密理博,17-131,Src Assay Kit

    产品名称：Src Assay Kit
    产品型号：17-131
    The radioactive Src Assay Kit is designed to measure the phosphotransferase activity of Src kinase in immunoprecipitates & column fractions.

    merck millipore,默克密理博,17-131,Src Assay Kit

  • 产品介绍
  • merck millipore,默克密理博,17-131,Src Assay Kit

    重要规格表

    主要应用 可用的分析物 检测方法
    KASrcRadioactive
    描述
    产品目录编号 17-131
    品牌系列 Upstate
    商名
    • Upstate
    描述 Src Assay Kit
    产品信息
    部件
    • P81 Phosphocellulose Squares (Cat.# 20-134)
    • Src Kinase Reaction Buffer (Cat.# 20-121)
    • Src Substrate Peptide (Cat.# 12-140)
    • Src Manganese/ATP Cocktail (Cat.# 20-110)
    检测方法 Radioactive
    应用
    应用 The radioactive Src Assay Kit is designed to measure the phosphotransferase activity of Src kinase in immunoprecipitates & column fractions.
    主要应用
    • Kinase Assay
    生物信息
    可用的分析物
    • Src
    Entrez基因编号
    • NM_198291.1
    • NM_005417.3
    Entrez基因汇总 This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
    基因符号
    • pp60c-src
    • SRC
    • ASV
    • c-src
    • p60-Src
    • SRC1
    • c-SRC
    UniProt编号
    • P12931
    UniProt汇总 SIZE: 536 amino acids; 59835 Da
    SUBUNIT: Interacts with DDEF1/ASAP1 via its SH3 domain. Interacts with CCPG1 (By similarity). Interacts with CDCP1, PELP1, TGFB1I1 and TOM1L2.
    PTM: Phosphorylated on Tyr-530 by c-Src kinase (CSK). The phosphorylated form is termed pp60c-src. The phosphorylated tail interacts with the SH2 domain thereby repressing kinase activity.
    SIMILARITY: SwissProt: P12931 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily. & Contains 1 protein kinase domain. & Contains 1 SH2 domain. & Contains 1 SH3 domain.
    产品使用声明
    质量保证 Routinely evalauted by phosphorylation of Src Substrate Peptide
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    包装信息
    数量 1 kit

    merck millipore,默克密理博,17-131,Src Assay Kit

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