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merck millipore,默克密理博,16-228,Anti-Cortactin (p80/85) Antibody, clone 4F11, Alexa Fluor 488
产品名称：Anti-Cortactin (p80/85) Antibody, clone 4F11, Alexa Fluor 488
产品型号：16-228
Detect Cortactin (p80/85) using this Anti-Cortactin (p80/85) Antibody, clone 4F11, Alexa Fluor 488 validated for use in FC, IF, WB & IC.
merck millipore,默克密理博,16-228,Anti-Cortactin (p80/85) Antibody, clone 4F11, Alexa Fluor 488
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, Av, B, H, Ht, M ICC, FC, WB M AlexaFluor®488 Monoclonal Antibody 描述 产品目录编号 16-228 品牌系列 Upstate
商名 - Upstate
描述 Anti-Cortactin (p80/85) Antibody, clone 4F11, Alexa Fluor® 488 产品信息 格式 AlexaFluor®488 应用 应用 Detect Cortactin (p80/85) using this Anti-Cortactin (p80/85) Antibody, clone 4F11, Alexa Fluor 488 validated for use in FC, IF, WB & IC. 主要应用 - Immunocytochemistry
- Flow Cytometry
- Western Blotting
生物信息 免疫原品种 Mixture of affinity-purified tyrosine phosphoproteins from chick embryo fibroblasts expressing activated pp60src 克隆 clone 4F11 宿主 Mouse 特异性 Recognizes Cortactin in rodent and human cells 同种型 IgG1 品种反应性 RatAvianBovineHumanHamsterMouse 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_138565.1
- NM_005231.2
Entrez基因汇总 This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Two splice variants that encode different isoforms have been identified for this gene. 基因符号 - FLJ34459
- CTTN
- EMS1
- Amplaxin
- 1110020L01Rik
修改 - Phosphorylation
纯化方法 Protein G purfied UniProt编号 - Q14247
UniProt汇总 FUNCTION: SwissProt: Q14247 # May contribute to the organization of cell structure. The SH3 motif may function as a binding region to cytoskeleton. Tyrosine phosphorylation in transformed cells may contribute to cellular growth regulation and transformation.
SIZE: 550 amino acids; 61636 Da
SUBUNIT: Interacts with SHANK2 and SHANK3 via its SH2 domain. Also interacts with FGD1 (By similarity). Interacts with PLXDC2.
SUBCELLULAR LOCATION: Cytoplasm (By similarity). Cell projection, lamellipodium (By similarity). Cell projection, ruffle (By similarity). Note=Associated with membrane ruffles and lamellipodia (By similarity).
SIMILARITY: SwissProt: Q14247 ## Contains 7 cortactin repeats. & Contains 1 SH3 domain.产品使用声明 质量保证 Routinely evaluated by immunoblot. 使用声明 - Alexa Fluor® is a registered trademark of Molecular Probes, Inc.
- Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 1 year at 4°C from date of shipment 包装信息 数量 100 µg
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