merck millipore,默克密理愽
  • merck millipore,默克密理博,MAB5628,Anti-Glial Fibrillary Acidic Protein Antibody

  • merck millipore,默克密理博,MAB5628,Anti-Glial Fibrillary Acidic Protein Antibody

    产品名称：Anti-Glial Fibrillary Acidic Protein Antibody
    产品型号：MAB5628
    Detect Glial Fibrillary Acidic Protein using this Anti-Glial Fibrillary Acidic Protein Antibody validated for use in WB & IC.

    merck millipore,默克密理博,MAB5628,Anti-Glial Fibrillary Acidic Protein Antibody

  • 产品介绍
  • merck millipore,默克密理博,MAB5628,Anti-Glial Fibrillary Acidic Protein Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, HICC, WBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MAB5628
    Replaces 04-1031; 04-1062
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Glial Fibrillary Acidic Protein Antibody
    Alternate Names
    • GFAP
    产品信息
    格式 Purified
    控制
    • Positive: Neural tissue or astrocyte culture
      Negative: Non-neural tissue or neuronal culture
    演示 Purified immunoglobulin. Liquid in 0.02M phosphate buffer, 0.25 M NaCl, pH 7.6 with 0.1% sodium azide.
    应用
    应用 Detect Glial Fibrillary Acidic Protein using this Anti-Glial Fibrillary Acidic Protein Antibody validated for use in WB & IC.
    主要应用
    • Immunocytochemistry
    • Western Blotting
    应用说明 Western blot: 1:10,000 on rat brain

    Optimal working dilutions must be determined by end user.
    生物信息
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    同种型 IgG2a
    品种反应性 RatHuman
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_002055.2
    Entrez基因汇总 This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. An additional transcript variant has been described, but its full length sequence has not been determined.
    基因符号
    • FLJ45472
    • GFAP
    UniProt编号
    • P14136
    UniProt汇总 FUNCTION: SwissProt: P14136 # GFAP, a class-III intermediate filament, is a cell- specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
    SIZE: 432 amino acids; 49880 Da
    SUBUNIT: Isoform 3 interacts with N-terminus of PSEN1.
    SUBCELLULAR LOCATION: Cytoplasm. Note=Associated with intermediate filaments.
    DISEASE: SwissProt: P14136 # Defects in GFAP are a cause of Alexander disease [MIM:203450]. Alexander disease is a rare disorder of the central nervous system. It is a progressive leukoencephalopathy whose hallmark is the widespread accumulation of Rosenthal fibers which are cytoplasmic inclusions in astrocytes. The most common form affects infants and young children, and is characterized by progressive failure of central myelination, usually leading to death usually within the first decade. Infants with Alexander disease develop a leukoencephalopathy with macrocephaly, seizures, and psychomotor retardation. Patients with juvenile or adult forms typically experience ataxia, bulbar signs and spasticity, and a more slowly progressive course.
    SIMILARITY: SwissProt: P14136 ## Belongs to the intermediate filament family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MAB5628,Anti-Glial Fibrillary Acidic Protein Antibody

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