merck millipore,默克密理博,14-924,TYK2 Protein, active, 10 µg

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Merck Millipore 默克密理愽

描述
产品目录编号	14-924
商名	Upstate
描述	TYK2 Protein, active, 10 µg
概述	TYK2 is member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.

产品信息
演示	50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol

应用
应用	Active, TN-terminal 6His-tagged, recombinant, human TYK2, amino acids 875-end. For use in Kinase Assays.
主要应用	Kinase Assay

生物信息
来源	N-terminal 6His-tagged, recombinant, human TYK2 amino acids 875-end, expressed by baculovirus in Sf21 insect cells.
品种	Human
特异活性	For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez基因编号	NM_003331
基因符号	JTK1 TYK2
蛋白靶	TYK2
纯化方法	Purified using immobilized metal affinity chromatography followed by gel filtration.
靶子系列	TK
UniProt编号	P29597

产品使用声明
质量保证	Routinely evaluated by phosphorylation of peptide GGMEDIYFEFMGGKKK
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	6 months at -70°C

包装信息
数量	10 µg
包装	Also available in 250μg size as catalog # 14-924M and in bulk as catalog # 14-924-K.

merck millipore,默克密理博,14-924,TYK2 Protein, active, 10 µg

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