merck millipore,默克密理愽
  • merck millipore,默克密理博,14-783,PI3 Kinase (p110α(E545K)/p85α), 10 µg

  • merck millipore,默克密理博,14-783,PI3 Kinase (p110α(E545K)/p85α), 10 µg

    产品名称：PI3 Kinase (p110α(E545K)/p85α), 10 µg
    产品型号：14-783
    Complex of N-terminal 6His-tagged, recombinant, full-length human p110α containing the mutation E545K & untagged, recombinant, full-length human p85α. For use in Kinase Assays.

    merck millipore,默克密理博,14-783,PI3 Kinase (p110α(E545K)/p85α), 10 µg

  • 产品介绍
  • merck millipore,默克密理博,14-783,PI3 Kinase (p110α(E545K)/p85α), 10 µg

    描述
    产品目录编号 14-783
    商名
    • Upstate
    描述 PI3 Kinase (p110α(E545K)/p85α), 10 µg
    概述 Complex of N-terminal 6His-tagged, recombinant, full-length human p110α containing the mutation E545K and untagged, recombinant, full-length human p85α.
    背景信息 The E545K substitution is a somatic mutation in p110α that has been associated with tumours of the colon and brain. Combined in vitro and in vivo studies have shown that this mutation confers higher lipid kinase activity than wild type, and is able to induce oncogenic transformation.
    应用
    应用 Complex of N-terminal 6His-tagged, recombinant, full-length human p110α containing the mutation E545K & untagged, recombinant, full-length human p85α. For use in Kinase Assays.
    主要应用
    • Kinase Assay
    生物信息
    来源 Coexpressed by baculovirus in Sf21 insect cells.
    品种 Human
    特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
    Entrez基因编号
    • NM_006218.2
    Entrez基因汇总 Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers.
    基因符号
    • MGC142163
    • PIK3CA
    • PI3K
    • MGC142161
    • p110-alpha
    蛋白靶 PI3Kα/p85α
    纯化方法 Ni2+/NTA-agarose
    靶子系列 PI3K/PI4K
    UniProt编号
    • P42336
    UniProt汇总 FUNCTION: SwissProt: P42336 # Phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2 with a preference for PtdIns(4,5)P2.
    SIZE: 1068 amino acids; 124284 Da
    SUBUNIT: Heterodimer of a p110 (catalytic) and a p85 (regulatory) subunit. Binds to IRS1 in nuclear extracts. Interacts with RUFY3 (By similarity).
    DISEASE: SwissProt: P42336 # Defects in PIK3CA are associated with colorectal cancer (CRC) [MIM:114500]. & Defects in PIK3CA are associated with breast cancer [MIM:114480]. & Defects in PIK3CA are associated with epithelial ovarian cancer (EOC) [MIM:604370].
    SIMILARITY: SwissProt: P42336 ## Belongs to the PI3/PI4-kinase family. & Contains 1 C2 domain. & Contains 1 PI3K/PI4K domain.
    储存和货运信息
    存储条件 Store at -70°C from date of shipment. For maximum recovery of product, centrifuge original vial prior to removing the cap.

    Rapidly thaw the vial under cold water and immediately place on ice. Aliquot unused material into pre-chilled microcentrifuge tubes and immediately snap-freeze the vials in liquid nitrogen prior to re-storage at -70°C.
    包装信息
    数量 10 µg
    包装 Also available in 250 μg size --call for pricing and availability and reference catalog number 14-783M when ordering the 250 μg size.

    merck millipore,默克密理博,14-783,PI3 Kinase (p110α(E545K)/p85α), 10 µg

上一件merck millipore产品：merck millipore,默克密理博,AP106A,Rabbit Anti-Goat IgG Antibody, Alkaline Phosphatase conjugate
下一件merck millipore产品：merck millipore,默克密理博,06-1376,Anti-SLBP Antibody


相关产品

merck millipore,默克密理博,SF-3198,SLC27A5; Human, Cyanine 5 RNA Detection Probe,SmartFlare merck millipore,默克密理博,SF-3198,SLC27A5; Human, Cyanine 5 RNA Detection Probe,SmartFlare

merck millipore,默克密理博,05-23-0101,Angiotensin II, Human - CAS 4474-91-3 - Calbiochem merck millipore,默克密理博,05-23-0101,Angiotensin II, Human - CAS 4474-91-3 - Calbiochem

merck millipore,默克密理博,MABF272,Anti-TREM-1, clone 2(1a2) Antibody merck millipore,默克密理博,MABF272,Anti-TREM-1, clone 2(1a2) Antibody

merck millipore,默克密理博,06-227,Anti-TGFβR Type II Antibody, NT merck millipore,默克密理博,06-227,Anti-TGFβR Type II Antibody, NT

merck millipore,默克密理博,AP106A,Rabbit Anti-Goat IgG Antibody, Alkaline Phosphatase conjugate merck millipore,默克密理博,AP106A,Rabbit Anti-Goat IgG Antibody, Alkaline Phosphatase conjugate

merck millipore,默克密理博,06-1376,Anti-SLBP Antibody merck millipore,默克密理博,06-1376,Anti-SLBP Antibody

merck millipore,默克密理博,204884,Complement C3a des-Arg, Human merck millipore,默克密理博,204884,Complement C3a des-Arg, Human

merck millipore,默克密理博,SF-1442,Agrin; Mouse, Cyanine 5 RNA Detection Probe,SmartFlare merck millipore,默克密理博,SF-1442,Agrin; Mouse, Cyanine 5 RNA Detection Probe,SmartFlare

merck millipore,默克密理博,178462,Apolipoprotein C-II, Human Plasma, Very Low-Density Lipoprotein merck millipore,默克密理博,178462,Apolipoprotein C-II, Human Plasma, Very Low-Density Lipoprotein

merck millipore,默克密理博,14-718,CaM Kinase IIβ Protein, active, 10 µg merck millipore,默克密理博,14-718,CaM Kinase IIβ Protein, active, 10 µg


whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部