merck millipore,默克密理愽
  • merck millipore,默克密理博,14-718,CaM Kinase IIβ Protein, active, 10 µg

  • merck millipore,默克密理博,14-718,CaM Kinase IIβ Protein, active, 10 µg

    产品名称：CaM Kinase IIβ Protein, active, 10 µg
    产品型号：14-718
    Active, N-terminal 6His-tagged, recombinant, CaM Kinase IIβ, amino acids 1-315, for use in Kinase Assays.

    merck millipore,默克密理博,14-718,CaM Kinase IIβ Protein, active, 10 µg

  • 产品介绍
  • merck millipore,默克密理博,14-718,CaM Kinase IIβ Protein, active, 10 µg

    描述
    产品目录编号 14-718
    品牌系列 Upstate
    商名
    • Upstate
    描述 CaM Kinase IIβ Protein, active, 10 µg
    概述 N-terminal 6His-tagged, recombinant, CaM Kinase IIβ, amino acids 1-315
    应用
    应用 Active, N-terminal 6His-tagged, recombinant, CaM Kinase IIβ, amino acids 1-315, for use in Kinase Assays.
    主要应用
    • Kinase Assay
    生物信息
    来源 expressed by baculovirus in Sf21 cells
    品种 Human
    特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
    Entrez基因编号
    • NM_172084.1
    • NM_001220.3
    • NM_172078.1
    • NM_172079.1
    • NM_172080.1
    • NM_172081.1
    • NM_172082.1
    • NM_172083.1
    Entrez基因汇总 The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Eight transcript variants encoding eight distinct isoforms have been identified for this gene.
    基因符号
    • CAMK2
    • CAMK2B
    • CAMKB
    • CAM2
    • MGC29528
    蛋白靶 CaMKIIβ
    纯化方法 Ni2+/NTA-agarose
    靶子系列 CAMK
    UniProt编号
    • Q13554
    UniProt汇总 FUNCTION: SwissProt: Q13554 # CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity).
    SIZE: 664 amino acids; 72727 Da
    SUBUNIT: CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Interacts with SYNGAP1 (By similarity). Interacts with MPDZ.
    TISSUE SPECIFICITY: Widely expressed. Expressed in adult and fetal brain. Expression islightly lower in fetal brain.
    SIMILARITY: SwissProt: Q13554 ## Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily. & Contains 1 protein kinase domain.
    产品使用声明
    质量保证 routinely evaluated by phosphorylation of 250μM ZIPtide (Catalog # 12-545)
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 6 months at -70°C from date of shipment
    包装信息
    数量 10 µg

    merck millipore,默克密理博,14-718,CaM Kinase IIβ Protein, active, 10 µg

上一件merck millipore产品：merck millipore,默克密理博,178462,Apolipoprotein C-II, Human Plasma, Very Low-Density Lipoprotein
下一件merck millipore产品：merck millipore,默克密理博,344960,FUT-175 - CAS 82956-11-4 - Calbiochem


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