merck millipore,默克密理愽
  • merck millipore,默克密理博,14-770,mTOR (1362-end) Protein, active, 10 µg

  • merck millipore,默克密理博,14-770,mTOR (1362-end) Protein, active, 10 µg

    产品名称：mTOR (1362-end) Protein, active, 10 µg
    产品型号：14-770
    Active, N-terminal FLAG-tagged, recombinant, human mTOR, amino acids 1362-end, for use in Kinase Assays.

    merck millipore,默克密理博,14-770,mTOR (1362-end) Protein, active, 10 µg

  • 产品介绍
  • merck millipore,默克密理博,14-770,mTOR (1362-end) Protein, active, 10 µg

    描述
    产品目录编号 14-770
    品牌系列 Upstate
    商名
    • Upstate
    描述 mTOR (1362-end) Protein, active, 10 µg
    概述 N-terminal FLAG-tagged, recombinant, human mTOR, amino acids 1362-end
    Alternate Names
    • FRAP1
    产品信息
    演示 16µg of enzyme in 100µl of 10mM HEPES, 50mM NaCl, 50mM β-glycerophosphate, 0.25mM sodium orthovanadate, 10mM NaF, 300µg/ml FLAGTM peptide, 20% v/v glycerol
    应用
    应用 Active, N-terminal FLAG-tagged, recombinant, human mTOR, amino acids 1362-end, for use in Kinase Assays.
    主要应用
    • Kinase Assay
    生物信息
    品种 Human
    特异活性 377Units/mg, where one unit of mTOR activity is defined as 1 nmole of phosphate incorporated into 2mg/ml mTOR substrate per minute at 30°C with a final ATP concentration of 100µM.
    Entrez基因编号
    • NM_004958.2
    Entrez基因汇总 The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The CDT6 gene is located in an intron of this gene.
    基因符号
    • RAFT1
    • FRAP1
    • RAPT1
    • MTOR
    • FRAP
    • mTOR
    • FLJ44809
    • FRAP2
    蛋白靶 mTOR (FRAP1)
    靶子系列 Lipid/Atypical
    UniProt编号
    • P42345
    UniProt汇总 FUNCTION: SwissProt: P42345 # Acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. Part of the TORC2 complex which plays a critical role in AKT1 Ser-473 phosphorylation, and may modulate the phosphorylation of PKCA and regulate actin cytoskeleton organization.
    SIZE: 2549 amino acids; 288892 Da
    SUBUNIT: Interacts with the FKBP12-rapamycin complex. Binds UBQLN1. Forms part of the mammalian target of rapamycin 2 complex (TORC2) comprised of FRAP1, GBL, PRR5, RICTOR and SIN. TORC2 does not bind to and is not sensitive to FKBP12-rapamycin. Binds directly to PRR5 and RICTOR within the TORC2 complex.
    TISSUE SPECIFICITY: Expressed in numerous tissues, with highest levels in testis.
    SIMILARITY: SwissProt: P42345 ## Belongs to the PI3/PI4-kinase family. & Contains 1 FAT domain. & Contains 1 FATC domain. & Contains 7 HEAT repeats. & Contains 1 PI3K/PI4K domain.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Store -70°C. For maximum recovery of product, centrifuge original vial prior to removing the cap.
    包装信息
    数量 10 µg
    包装 Also available in 100μg size, please inquire for pricing and availability.

    merck millipore,默克密理博,14-770,mTOR (1362-end) Protein, active, 10 µg

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下一件merck millipore产品：merck millipore,默克密理博,AB15275,Anti-dsr-2 Antibody [D-serine-responsive transcript-2]


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