merck millipore,默克密理愽
  • merck millipore,默克密理博,14-633,PAK6 Protein, active, 10 µg

  • merck millipore,默克密理博,14-633,PAK6 Protein, active, 10 µg

    产品名称：PAK6 Protein, active, 10 µg
    产品型号：14-633
    Active, N-terminal His6-tagged, recombinant, human PAK6, amino acids 382-end, for use in Kinase Assays.

    merck millipore,默克密理博,14-633,PAK6 Protein, active, 10 µg

  • 产品介绍
  • merck millipore,默克密理博,14-633,PAK6 Protein, active, 10 µg

    描述
    产品目录编号 14-633
    品牌系列 Upstate
    商名
    • Upstate
    描述 PAK6 Protein, active, 10 µg
    概述 N-terminal His6-tagged, recombinant, human PAK6, amino acids 382-end
    应用
    应用 Active, N-terminal His6-tagged, recombinant, human PAK6, amino acids 382-end, for use in Kinase Assays.
    主要应用
    • Kinase Assay
    生物信息
    来源 baculovirus in Sf21 cells
    品种 Human
    特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
    Entrez基因编号
    • NM_020168.3
    Entrez基因汇总 This gene encodes a protein that shares a high degree of sequence similarity with p21-activated kinase (PAK) family members. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. The p21-activated protein kinase 6 gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen.
    基因符号
    • PAK5
    • PAK6
    • PAK-5
    • PAK-6
    蛋白靶 PAK6
    纯化方法 Ni2+/NTA-agarose
    靶子系列 STE
    UniProt编号
    • Q9NQU5
    UniProt汇总 FUNCTION: SwissProt: Q9NQU5 # The activated kinase acts on a variety of targets (By similarity).
    SIZE: 681 amino acids; 74869 Da
    SUBUNIT: Interacts tightly with GTP-bound but not GDP-bound CDC42/p21 and RAC1 (By similarity). Interacts with the androgen receptor.
    PTM: Autophosphorylated when activated by CDC42/p21 (By similarity).
    SIMILARITY: SwissProt: Q9NQU5 ## Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. & Contains 1 CRIB domain. & Contains 1 protein kinase domain.
    产品使用声明
    质量保证 routinely evaluated by phosphorylation of PAKtide
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 6 months at -70°C
    包装信息
    数量 10 µg

    merck millipore,默克密理博,14-633,PAK6 Protein, active, 10 µg

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