- 当前位置:首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H, M WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB2265 描述 Anti-VPAC1 Antibody Alternate Names - vasoactive intestinal peptide/pituitary adenylate cyclase activating peptide receptor 1
- Vasoactive intestinal polypeptide receptor 1
- Pituitary adenylate cyclase-activating polypeptide type II receptor
背景信息 The vasoactive intestinal peptide/pituitary adenylate cyclase activating peptide receptor 1 (VPAC1) is a member of a class II subfamily of G-protein-coupled receptors and has a high affinity for vasoactive intestinal peptide (VIP). VPAC1 has been associated with many different lung cancer cell lines. VPAC1 is thought to be activated by FXR and may contribute to the regulation of bile secretion to protect against gallstone disease. VPAC1 could be used to regulate VIPs and, in turn, inhibit breast cancer growth. VPAC1 has also been implicated in regulation of the anti-inflammatory effects of VIP. 产品信息 格式 Affinity Purified 控制 - SK-OV-3 cell lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-VPAC1 Antibody detects level of VPAC1 & has been published & validated for use in IH(P) & WB. 主要应用 - Western Blotting
应用说明 Immunohistochemistry Analysis: 1:500 dilution from a previous lot detected VPAC1 in ovarian carcinoma tissue. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to the cytoplasmic domain of VPAC1. 表位 Cytoplasmic domain 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes VPAC1 at the cytoplasmic domain. 品种反应性 RatHumanMouse Species Reactivity Note Demonstrated to react with human, mouse, and rat. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_035833
基因符号 - RDC1
- VIPR1
- PACAP-R-2
- RCD1
- VIP-R-1
- VPAC1
- VIRG
- HVR1
- VPCAP1R
- VAPC1
- VIPR
纯化方法 Affinity purified UniProt编号 - P97751
UniProt汇总 FUNCTION: This is a receptor for VIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
SEQUENCE SIMILARITIES: Belongs to the G-protein coupled receptor 2 family.产品使用声明 质量保证 Evaluated by Western Blot in SK-OV-3 cell lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected VPAC1 on 10 µg of SK-OV-3 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
上一件merck millipore产品:merck millipore,默克密理博,14-633,PAK6 Protein, active, 10 µg
下一件merck millipore产品:merck millipore,默克密理博,70005,T7SelectUP Primer
merck millipore,默克密理博,AB15275,Anti-dsr-2 Antibody [D-serine-responsive transcript-2]
merck millipore,默克密理博,ABN264,Anti-HEXB Antibody
merck millipore,默克密理博,SF-112,HPRT1; Rat, Cyanine 3, RNA Detection Probe,SmartFlare
merck millipore,默克密理博,SF-2334,TCF3; Human, Cyanine 5 RNA Detection Probe,SmartFlare
merck millipore,默克密理博,14-633,PAK6 Protein, active, 10 µg
merck millipore,默克密理博,70005,T7SelectUP Primer
merck millipore,默克密理博,12-421,MYPT1, (714-1004)
merck millipore,默克密理博,126621,Albumin, Bovine Serum, Cohn Fraction, 30% Aqueous Solution
merck millipore,默克密理博,MAB4306,Anti-Human Leukemia Inhibitory Factor Antibody, clone 4F7.2




