merck millipore,默克密理愽
  • merck millipore,默克密理博,373401,Hh/Gli Antagonist, GANT61 - CAS 500579-04-4 - Calbiochem

  • merck millipore,默克密理博,373401,Hh/Gli Antagonist, GANT61 - CAS 500579-04-4 - Calbiochem

    产品名称：Hh/Gli Antagonist, GANT61 - CAS 500579-04-4 - Calbiochem
    产品型号：373401
    The Hh/Gli Antagonist, GANT61, also referenced under CAS 500579-04-4, controls the biological activity of Hh/Gli. This small molecule/inhibitor is primarily used for Cell Signaling applications.

    merck millipore,默克密理博,373401,Hh/Gli Antagonist, GANT61 - CAS 500579-04-4 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,373401,Hh/Gli Antagonist, GANT61 - CAS 500579-04-4 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₇H₃₅N₅500579-04-4
    描述
    概述 A cell-permeable hexahydropyrimidine compound that displays similar pharmacological property as, but is structurally disctinct from, GANT58 (Cat. No. 373400). While both compounds act as downstream Hedgehog (Hh) pathway-selective blockers and target Gli-mediated gene transactivation with similar potency (IC50 = ~ 5 µM) in SAG-stimulated Shh-L2 cells, GANT61 does exhibit better in vivo antitumor efficacy, presumably due to its superior pharmacokinetics, and only GANT61, but not GANT58, is shown to inhibit Gli DNA binding in HEK293 cells. Also available as a 25 mM solution in DMSO (Cat. No. 373403).
    产品目录编号 373401
    品牌系列 Calbiochem®
    同义词 2-((3-(2-(Dimethylamino)benzyl)-2-(4-pyridinyl)tetrahydro-1(2H)-pyrimidinyl)methyl)-N,N-dimethylaniline, NSC 136476
    参考
    参考 Lauth, M., et al. 2007. Proc. Natl. Acad. Sci. USA 104, 8455.
    产品信息
    CAS号 500579-04-4
    形式 Off-white solid
    Hill配方 C₂₇H₃₅N₅
    化学配方 C₂₇H₃₅N₅
    Molar Mass 429.6
    结构配方图像
    生物信息
    纯度 ≥95% by HPLC
    理化信息
    溶解度 DMSO or EtOH
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,373401,Hh/Gli Antagonist, GANT61 - CAS 500579-04-4 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,07-2068,Anti-PRDM2 Antibody (RIZ1)
下一件merck millipore产品：merck millipore,默克密理博,FCMAB390F,Milli-Mark Anti-pan Histone-FITC Antibody, clone H11-4


相关产品

merck millipore,默克密理博,400122,Human IgG₂, Myeloma merck millipore,默克密理博,400122,Human IgG₂, Myeloma

merck millipore,默克密理博,CBL242,Anti-Glucose Transporter GLUT-1 Antibody, CT merck millipore,默克密理博,CBL242,Anti-Glucose Transporter GLUT-1 Antibody, CT

merck millipore,默克密理博,4000-0061,Guava Express 7-AAD Reagent for Flow Cytometry merck millipore,默克密理博,4000-0061,Guava Express 7-AAD Reagent for Flow Cytometry

merck millipore,默克密理博,SF005,ESGRO Complete Serum-Free Cell Culture Freezing Medium; 50 mL merck millipore,默克密理博,SF005,ESGRO Complete Serum-Free Cell Culture Freezing Medium; 50 mL

merck millipore,默克密理博,07-2068,Anti-PRDM2 Antibody (RIZ1) merck millipore,默克密理博,07-2068,Anti-PRDM2 Antibody (RIZ1)

merck millipore,默克密理博,FCMAB390F,Milli-Mark Anti-pan Histone-FITC Antibody, clone H11-4 merck millipore,默克密理博,FCMAB390F,Milli-Mark Anti-pan Histone-FITC Antibody, clone H11-4

merck millipore,默克密理博,05-719,Anti-Phosphatidylserine Antibody, clone 1H6 merck millipore,默克密理博,05-719,Anti-Phosphatidylserine Antibody, clone 1H6

merck millipore,默克密理博,05-1410,Anti-CD45 Antibody, clone F10-89-4 merck millipore,默克密理博,05-1410,Anti-CD45 Antibody, clone F10-89-4

merck millipore,默克密理博,14-770,mTOR (1362-end) Protein, active, 10 µg merck millipore,默克密理博,14-770,mTOR (1362-end) Protein, active, 10 µg

merck millipore,默克密理博,AB15275,Anti-dsr-2 Antibody [D-serine-responsive transcript-2] merck millipore,默克密理博,AB15275,Anti-dsr-2 Antibody [D-serine-responsive transcript-2]


whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部