merck millipore,默克密理愽
  • merck millipore,默克密理博,CBL242,Anti-Glucose Transporter GLUT-1 Antibody, CT

  • merck millipore,默克密理博,CBL242,Anti-Glucose Transporter GLUT-1 Antibody, CT

    产品名称：Anti-Glucose Transporter GLUT-1 Antibody, CT
    产品型号：CBL242
    Anti-Glucose Transporter GLUT-1 Antibody, C-terminus detects level of Glucose Transporter GLUT-1 & has been published & validated for use in IP & WB.

    merck millipore,默克密理博,CBL242,Anti-Glucose Transporter GLUT-1 Antibody, CT

  • 产品介绍
  • merck millipore,默克密理博,CBL242,Anti-Glucose Transporter GLUT-1 Antibody, CT

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, H, MWBRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 CBL242
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Glucose Transporter GLUT-1 Antibody, CT
    产品信息
    格式 Affinity Purified
    控制
    • Colorectal carcinoma
    演示 The polyclonal is presented in phosphate buffered saline containing 10mM sodium azide. We recommend that each laboratory determine an optimum working titre for use in its particular application.
    应用
    应用 Anti-Glucose Transporter GLUT-1 Antibody, C-terminus detects level of Glucose Transporter GLUT-1 & has been published & validated for use in IP & WB.
    主要应用
    • Western Blotting
    应用说明 Western blot analysis of GLUT-1 activity in adipose and muscle tissue (5μg/ml)

    Immunoprecipitation of GLUT-1 (5μg/ml)

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 12 amino acid peptide of the C-terminus of hGLUT-1 {LFHPLGADSQV} conjugated to KLH
    表位 C-terminus
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Specific for human glucose transporter 1 from muscle and adipose tissue. Does not cross-react with GLUT-4. The molecular weight of the glucose transporter precipitated by the serum is approximately 46 kDa.
    品种反应性 RatHumanMouse
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_006516.1
    Entrez基因汇总 Glucose transporters are integral membrane glycoproteins involved in transporting glucose into most cells. GLUT1 is a major glucose transporter in the mammalian blood-brain barrier. It is present at high levels in primate erythrocytes and brain endothelial cells.[supplied by OMIM]
    基因符号
    • GLUT
    • SLC2A1
    • GLUT-1
    • MGC141896
    • GLUT1
    • MGC141895
    纯化方法 Immunoaffinity purified
    UniProt编号
    • P11166
    UniProt汇总 FUNCTION: SwissProt: P11166 # Facilitative glucose transporter. This isoform may be responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses.
    SIZE: 492 amino acids; 54084 Da
    SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein (By similarity). Melanosome. Note=Localizes primarily at the cell surface (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
    TISSUE SPECIFICITY: Expressed at variable levels in many human tissues.
    PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.
    DISEASE: SwissProt: P11166 # Defects in SLC2A1 are the cause of autosomal dominant GLUT1 deficiency syndrome [MIM:606777]. This disease causes a defect in glucose transport across the blood-brain barrier. It is characterized by infantile seizures, delayed development, and acquired microcephaly.
    SIMILARITY: SwissProt: P11166 ## Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 For use within 1 month of purchase store at +4°C, for long term storage aliquot antibody into small volumes and store at -20°C for up to one year.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,CBL242,Anti-Glucose Transporter GLUT-1 Antibody, CT

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