merck millipore,默克密理愽
  • merck millipore,默克密理博,14-723M,CaM Kinase IIδ Protein, active, 250 µg

  • merck millipore,默克密理博,14-723M,CaM Kinase IIδ Protein, active, 250 µg

    产品名称：CaM Kinase IIδ Protein, active, 250 µg
    产品型号：14-723M
    Active, N-terminal 6His-tagged, recombinant, human, full length CaM Kinase IIδ, for use in Kinase Assays.

    merck millipore,默克密理博,14-723M,CaM Kinase IIδ Protein, active, 250 µg

  • 产品介绍
  • merck millipore,默克密理博,14-723M,CaM Kinase IIδ Protein, active, 250 µg

    描述
    产品目录编号 14-723M
    品牌系列 Upstate
    商名
    • Upstate
    描述 CaM Kinase IIδ Protein, active, 250 µg
    概述 N-terminal 6His-tagged, recombinant, human, full length CaM Kinase IIδ

    N-terminal 6His-tagged, recombinant, human, full length CaM Kinase IIδ
    应用
    应用 Active, N-terminal 6His-tagged, recombinant, human, full length CaM Kinase IIδ, for use in Kinase Assays.
    主要应用
    • Kinase Assay
    生物信息
    来源 expressed by baculovirus in Sf21 cells
    品种 Human
    特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
    Entrez基因编号
    • NM_172128.1
    • NM_001221.2
    • NM_172115.1
    • NM_172127.1
    Entrez基因汇总 The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a delta chain. Four alternatively spliced transcript variants that encode three different isoforms have been characterized to date. Distinct isoforms of this chain have different expression patterns.
    基因符号
    • MGC44911
    • CAMK2D
    • CAMKD
    蛋白靶 CaMKIIδ
    纯化方法 Ni2+/NTA-agarose
    靶子系列 CAMK
    UniProt编号
    • Q13557
    UniProt汇总 FUNCTION: SwissProt: Q13557 # CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release.
    SIZE: 499 amino acids; 56369 Da
    SUBUNIT: CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits.
    TISSUE SPECIFICITY: Expressed in cardiac muscle and skeletal muscle. Isoform Delta 3, isoform Delta 2, isoform Delta 8 and isoform Delta 9 are expressed in cardiac muscle. Isoform Delta 11 is expressed in skeletal muscle.
    SIMILARITY: SwissProt: Q13557 ## Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily. & Contains 1 protein kinase domain.
    MISCELLANEOUS: Expression of CAMK2D is significantly increased in patients suffering from dilated cardiomyopathy.
    产品使用声明
    质量保证 routinely evaluated by phosphorylation of 250μM ZIPtide (Catalog # 12-545)
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 6 months at -70°C from date of shipment
    包装信息
    数量 250 µg
    包装 Also available in 10 μg size (cat#14-723) and in bulk (cat# 14-723-K).

    merck millipore,默克密理博,14-723M,CaM Kinase IIδ Protein, active, 250 µg

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